| Gene Symbol |
SEMA3B
|
| Entrez Gene |
7869
|
| Alt Symbol |
LUCA-1, SEMA5, SEMAA, SemA, semaV
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
|
| Other Description |
sema A(V)|semaphorin A|semaphorin-3B|semaphorin-V
|
| Swissprots |
Q96GX0 Q8TB71 Q93018 Q8TDV7 Q6GU46 Q13214
|
| Accessions |
AAC02731 CAD91051 CAI84572 EAW65062 EAW65063 EAW65064 EAW65065 EAW65066 EAW65067 Q13214 AB083186 BAB88870 AB209322 BAD92559 AF217991 AAG17234 AI309508 AK092182 BAC03823 AK098329 AK293678 BAG57120 AK308875 BC009113 AAH09113 BC013975 AAH13975 BC024220 AAH24220 BC044602 AAH44602 BI603095 DC330072 EU832609 ACE87700 EU832680 ACE87012 HY146744 HY152168 JF432761 ADZ15978 U28369 AAD09138 NM_001005914 NP_001005914 NM_001290060 NP_001276989 NM_001290061 NP_001276990 NM_001290062 NP_001276991 NM_001290063 NP_001276992 NM_004636 NP_004627 NR_110697
|
| Function |
Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. {ECO:0000250}.
|
| Subcellular Location |
Secreted {ECO:0000250}. Endoplasmic reticulum. Note=Accumulates in the endoplasmic reticulum.
|
| Tissue Specificity |
Expressed abundantly but differentially in a variety of neural and nonneural tissues.
|
| Top Pathways |
Axon guidance
|
![Western Blot: SEMA3B Overexpression Lysate (Adult Normal) [NBL1-15798] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SEMA3B.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8927_SEMA3B%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-15798-img0002.jpg)