SEMA3B
| Gene Symbol | SEMA3B |
|---|---|
| Entrez Gene | 7869 |
| Alt Symbol | LUCA-1, SEMA5, SEMAA, SemA, semaV |
| Species | Human |
| Gene Type | protein-coding |
| Description | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| Other Description | sema A(V)|semaphorin A|semaphorin-3B|semaphorin-V |
| Swissprots | Q96GX0 Q8TB71 Q93018 Q8TDV7 Q6GU46 Q13214 |
| Accessions | AAC02731 CAD91051 CAI84572 EAW65062 EAW65063 EAW65064 EAW65065 EAW65066 EAW65067 Q13214 AB083186 BAB88870 AB209322 BAD92559 AF217991 AAG17234 AI309508 AK092182 BAC03823 AK098329 AK293678 BAG57120 AK308875 BC009113 AAH09113 BC013975 AAH13975 BC024220 AAH24220 BC044602 AAH44602 BI603095 DC330072 EU832609 ACE87700 EU832680 ACE87012 HY146744 HY152168 JF432761 ADZ15978 U28369 AAD09138 NM_001005914 NP_001005914 NM_001290060 NP_001276989 NM_001290061 NP_001276990 NM_001290062 NP_001276991 NM_001290063 NP_001276992 NM_004636 NP_004627 NR_110697 |
| Function | Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. {ECO:0000250}. |
| Subcellular Location | Secreted {ECO:0000250}. Endoplasmic reticulum. Note=Accumulates in the endoplasmic reticulum. |
| Tissue Specificity | Expressed abundantly but differentially in a variety of neural and nonneural tissues. |
| Top Pathways | Axon guidance |
SEMA3B CRISPR/Cas9 KO Plasmid (h) - sc-402778 from Santa Cruz Biotechnology
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SEMA3B HDR Plasmid (h) - sc-402778-HDR from Santa Cruz Biotechnology
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SEMA3B Double Nickase Plasmid (h) - sc-402778-NIC from Santa Cruz Biotechnology
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SEMA3B Double Nickase Plasmid (h2) - sc-402778-NIC-2 from Santa Cruz Biotechnology
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SEMA3B CRISPR Activation Plasmid (h) - sc-402778-ACT from Santa Cruz Biotechnology
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SEMA3B CRISPR Activation Plasmid (h2) - sc-402778-ACT-2 from Santa Cruz Biotechnology
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SEMA3B Lentiviral Activation Particles (h) - sc-402778-LAC from Santa Cruz Biotechnology
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SEMA3B Lentiviral Activation Particles (h2) - sc-402778-LAC-2 from Santa Cruz Biotechnology
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SEMA3B siRNA (h) - sc-40934 from Santa Cruz Biotechnology
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SEMA3B shRNA Plasmid (h) - sc-40934-SH from Santa Cruz Biotechnology
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SEMA3B shRNA (h) Lentiviral Particles - sc-40934-V from Santa Cruz Biotechnology
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Semaphorin 3B RNAi - H00007869-R03 from Novus Biologicals
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MISSION® esiRNA - EHU140161 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19064 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19064 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05221 from Sigma-Aldrich
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SEMA3B siRNA (Human) - CRH5302 from Cohesion Biosciences
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Semaphorin 3B RNAi - H00007869-R04 from Novus Biologicals
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SEMA3B - MBS8226225 from MyBioSource
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shRNA set against Human SEMA3B (NM_004636.2) - SHH404196 from Creative biogene
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shRNA set against Human SEMA3B(NM_001005914.1) - SHR213576 from Creative biogene
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shRNA set against Human SEMA3B(NM_004636.2) - SHR213586 from Creative biogene
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shRNA set against Human SEMA3B(NM_001005914.1) - SHR213587 from Creative biogene
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shRNA set against Human SEMA3B(NM_004636.2) - SHR213588 from Creative biogene
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shRNA set against Human SEMA3B(NM_001005914.1) - SHR213589 from Creative biogene
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