| Gene Symbol | PKLR |
|---|---|
| Entrez Gene | 5313 |
| Alt Symbol | PK1, PKL, PKR, PKRL, RPK |
| Species | Human |
| Gene Type | protein-coding |
| Description | pyruvate kinase, liver and RBC |
| Other Description | R-type/L-type pyruvate kinase|pyruvate kinase 1|pyruvate kinase PKLR|pyruvate kinase isozyme R/L|pyruvate kinase isozymes L/R|pyruvate kinase isozymes R/L|pyruvate kinase type L|pyruvate kinase, liver and blood cell|red cell/liver pyruvate kinase |
| Swissprots | P11973 P30613 O75758 |
| Accessions | AAA92535 AAA92536 AAP69527 BAA02515 EAW53079 EAW53080 P30613 AB015983 BAA31706 AK225947 AK298399 BAG60632 BC025737 AAH25737 BF110802 EU176228 ABW03679 M15465 AAA60104 S60712 AAB26262 XM_005245266 XP_005245323 XM_006711386 XP_006711449 XM_006726212 XP_006726275 XM_011509639 XP_011507941 XM_011509640 XP_011507942 XM_011546931 XP_011545233 XM_011546932 XP_011545234 NM_000298 NP_000289 NM_181871 NP_870986 |
| Function | Plays a key role in glycolysis. {ECO:0000250}. |
| Top Pathways | Maturity onset diabetes of the young, Type II diabetes mellitus, Insulin signaling pathway, Non-alcoholic fatty liver disease (NAFLD), Glycolysis / Gluconeogenesis |