PKLR

Gene Symbol PKLR
Entrez Gene 5313
Alt Symbol PK1, PKL, PKR, PKRL, RPK
Species Human
Gene Type protein-coding
Description pyruvate kinase, liver and RBC
Other Description R-type/L-type pyruvate kinase|pyruvate kinase 1|pyruvate kinase PKLR|pyruvate kinase isozyme R/L|pyruvate kinase isozymes L/R|pyruvate kinase isozymes R/L|pyruvate kinase type L|pyruvate kinase, liver and blood cell|red cell/liver pyruvate kinase
Swissprots P11973 P30613 O75758
Accessions AAA92535 AAA92536 AAP69527 BAA02515 EAW53079 EAW53080 P30613 AB015983 BAA31706 AK225947 AK298399 BAG60632 BC025737 AAH25737 BF110802 EU176228 ABW03679 M15465 AAA60104 S60712 AAB26262 XM_005245266 XP_005245323 XM_006711386 XP_006711449 XM_006726212 XP_006726275 XM_011509639 XP_011507941 XM_011509640 XP_011507942 XM_011546931 XP_011545233 XM_011546932 XP_011545234 NM_000298 NP_000289 NM_181871 NP_870986
Function Plays a key role in glycolysis. {ECO:0000250}.
Top Pathways Maturity onset diabetes of the young, Type II diabetes mellitus, Insulin signaling pathway, Non-alcoholic fatty liver disease (NAFLD), Glycolysis / Gluconeogenesis

PKLR (D-14) - sc-68117 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PKLR (D-14): sc-68117. Western blot analysis of PKLR expression in non-transfected: sc-117752 (A) and human PKLR transfected: sc-114132 (B) 293T whole cell lysates.

PKLR (D-10) - sc-166228 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PKLR (D-10): sc-166228. Western blot analysis of PKLR expression in non-transfected: sc-117752 (A) and human PKLR transfected: sc-114132 (B) 293T whole cell lysates.

PKLR (G-11) - sc-133224 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PKLR (G-11): sc-133224. Western blot analysis of PKLR expression in non-transfected: sc-117752 (A) and human PKLR transfected: sc-114132 (B) 293T whole cell lysates.

PKLR (E-2) - sc-133222 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PKLR (E-2): sc-133222. Western blot analysis of PKLR expression in non-transfected: sc-117752 (A) and human PKLR transfected: sc-114132 (B) 293T whole cell lysates.

PKLR (S-14) - sc-68119 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PKLR (S-14): sc-68119. Western blot analysis of PKLR expression in non-transfected: sc-110760 (A) and human PKLR transfected: sc-114132 (B) 293T whole cell lysates.

PKLR (K-16) - sc-68118 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PKLR (K-16) : sc-68118. Western blot analysis of PKLR expression in non-transfected: sc-110760 (A) and human PKLR transfected: sc-114132 (B) 293T whole cell lysates.

Anti-PKLR antibody - ab38240 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-PKLR antibody (ab38240) at 1/100 dilution + NIH/3T3 cell lysate

Anti-PKLR antibody - ab137787 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PKLR antibody (ab137787) at 1/1000 dilutionLane 1 : Jurkat cell extract Lane 2 : Raji cell extract Lane 3 : K562 cell extract Lane 4 : THP-1 cell extract Lane 5 : NCI-H929 cell extractLysates/proteins at 30 µg per lane.

Anti-PKLR antibody - ab125697 from Abcam

Prices $384.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
ab125697, at 1/250 dilution, staining PKLR in Formalin-fixed, Paraffin-embedded Human breast cancer tissue by Immunohistochemistry.

Anti-PKLR antibody - ab89071 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-PKLR antibody (ab89071) at 1 µg/ml + Human liver tissue lysate at 50 µg

Anti-PKLR antibody - ab137851 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PKLR antibody (ab137851) at 1/500 dilution + HepG2 whole cell lysate at 30 µg

Anti-PKLR antibody [1A5] - ab117943 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1A5
All lanes : Anti-PKLR antibody [1A5] (ab117943) at 1/500 dilutionLane 1 : HEK293T cells were transfected with the pCMV6-ENTRY control cDNA for 48 hrs and lysed. Lane 2 : HEK293T cells were transfected with the pCMV6-ENTRY PKLR cDNA for 48 hrs and lysedLysates/proteins at 5 µg per lane.

Anti-PKLR antibody [1H9] - ab123908 from Abcam

Prices $384.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1H9
All lanes : Anti-PKLR antibody [1H9] (ab123908) at 1/2000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY controlLane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY PKLR cDNALysates/proteins at 5 µg per lane.

Anti-PKLR antibody [AT1E3] - ab119500 from Abcam

Prices $376.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone AT1E3
Anti-PKLR antibody [AT1E3] (ab119500) at 1/500 dilution + 293T cell lysate at 40 µgSecondarygoat anti-mouse HRPdeveloped using the ECL technique

Anti-PKLR antibody [EPR11093] - ab171744 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11093
Immunohistochemistry of paraffin-embedded Human liver tissue labeling PKLR using ab171744 at 1/250 dilution.

Anti-Pyruvate Kinase antibody - ab118499 from Abcam

Prices $378.00
Sizes 2.5 mg
Host Goat
Clonality Polyclonal
ab118499 at 5 &microg/ml staining Pyruvate Kinase in Human Pancreas by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.

Anti-PKLR Antibody (aa1-260) - LS-C186218 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded NCIN87 xenograft using Pyruvate Kinase (liver/RBC) antibody at 1:500 dilution.

Anti-PKLR Antibody (aa56-105) - LS-C80451 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
PKLR antibody LS-C80451 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.

Anti-PKLR Antibody (C-Terminus, AP) - LS-C281753 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PKLR Antibody (C-Terminus, APC) - LS-C281755 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PKLR Antibody (clone 1G9) - LS-C115406 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1G9
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PKLR (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PKLR.

Anti-PKLR Antibody (C-Terminus, Biotin) - LS-C281756 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PKLR Antibody (C-Terminus, FITC) - LS-C281757 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PKLR Antibody (C-Terminus, Azide-free, HRP) - LS-C281758 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PKLR Antibody (N-Terminus, AP) - LS-C281759 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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