| Gene Symbol |
RNF144A
|
| Entrez Gene |
9781
|
| Alt Symbol |
RNF144, UBCE7IP4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ring finger protein 144A
|
| Other Description |
E3 ubiquitin-protein ligase RNF144A|UbcM4-interacting protein 4|probable E3 ubiquitin-protein ligase RNF144A|ring finger protein 144|ubiquitin conjugating enzyme 7 interacting protein 4|ubiquitin-conjugating enzyme 7-interacting protein 4
|
| Swissprots |
D6W4Y6 Q585H5 P50876
|
| Accessions |
AAX82010 EAX01029 EAX01030 EAX01031 EAX01032 P50876 AK293854 BAG57251 BC035051 BC050373 AAH50373 BM550396 BM931543 BQ219370 BQ423668 BQ427820 BQ574061 CD101678 D79983 BAA11478 DA234807 EU446751 ABZ92280 XM_005246200 XP_005246257 XM_005246202 XP_005246259 XM_006711909 XP_006711972 XM_011510424 XP_011508726 NM_014746 NP_055561
|
| Function |
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates the ubiquitination and degradation of the DNA damage kinase PRKDC. {ECO:0000250, ECO:0000269|PubMed:24979766}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:24979766}; Single-pass membrane protein {ECO:0000305}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:24979766}.
|