Gene Symbol | RNF144A |
---|---|
Entrez Gene | 9781 |
Alt Symbol | RNF144, UBCE7IP4 |
Species | Human |
Gene Type | protein-coding |
Description | ring finger protein 144A |
Other Description | E3 ubiquitin-protein ligase RNF144A|UbcM4-interacting protein 4|probable E3 ubiquitin-protein ligase RNF144A|ring finger protein 144|ubiquitin conjugating enzyme 7 interacting protein 4|ubiquitin-conjugating enzyme 7-interacting protein 4 |
Swissprots | D6W4Y6 Q585H5 P50876 |
Accessions | AAX82010 EAX01029 EAX01030 EAX01031 EAX01032 P50876 AK293854 BAG57251 BC035051 BC050373 AAH50373 BM550396 BM931543 BQ219370 BQ423668 BQ427820 BQ574061 CD101678 D79983 BAA11478 DA234807 EU446751 ABZ92280 XM_005246200 XP_005246257 XM_005246202 XP_005246259 XM_006711909 XP_006711972 XM_011510424 XP_011508726 NM_014746 NP_055561 |
Function | E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates the ubiquitination and degradation of the DNA damage kinase PRKDC. {ECO:0000250, ECO:0000269|PubMed:24979766}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:24979766}; Single-pass membrane protein {ECO:0000305}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:24979766}. |
UBCE7IP4 CRISPR/Cas9 KO Plasmid (h) - sc-411343 from Santa Cruz Biotechnology
|
||||||||
UBCE7IP4 HDR Plasmid (h) - sc-411343-HDR from Santa Cruz Biotechnology
|
||||||||
UBCE7IP4 Double Nickase Plasmid (h) - sc-411343-NIC from Santa Cruz Biotechnology
|
||||||||
UBCE7IP4 Double Nickase Plasmid (h2) - sc-411343-NIC-2 from Santa Cruz Biotechnology
|
||||||||
UBCE7IP4 CRISPR Activation Plasmid (h) - sc-411343-ACT from Santa Cruz Biotechnology
|
||||||||
UBCE7IP4 CRISPR Activation Plasmid (h2) - sc-411343-ACT-2 from Santa Cruz Biotechnology
|
||||||||
UBCE7IP4 Lentiviral Activation Particles (h) - sc-411343-LAC from Santa Cruz Biotechnology
|
||||||||
UBCE7IP4 Lentiviral Activation Particles (h2) - sc-411343-LAC-2 from Santa Cruz Biotechnology
|
||||||||
UBCE7IP4 siRNA (h) - sc-94470 from Santa Cruz Biotechnology
|
||||||||
UBCE7IP4 shRNA Plasmid (h) - sc-94470-SH from Santa Cruz Biotechnology
|
||||||||
UBCE7IP4 shRNA (h) Lentiviral Particles - sc-94470-V from Santa Cruz Biotechnology
|
||||||||
RNF144A RNAi - H00009781-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU012801 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN18387 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18387 from Sigma-Aldrich
|
||||||||
RNF144A siRNA (Human) - CRH6543 from Cohesion Biosciences
|
||||||||
RNF144A - MBS8200268 from MyBioSource
|
||||||||
shRNA set against Human RNF144A (NM_014746.3) - SHH396772 from Creative biogene
|
||||||||
Human RNF144A siRNA - orb267045 from Biorbyt
|
||||||||
RNF144A shRNA Plasmid (Human) - CHH6543 from Cohesion Biosciences
|
||||||||
RNF144A miRNA 3'UTR clone - MiUTR1H-08882 from Creative biogene
|