| Gene Symbol | ITPR3 |
|---|---|
| Entrez Gene | 3710 |
| Alt Symbol | IP3R, IP3R3 |
| Species | Human |
| Gene Type | protein-coding |
| Description | inositol 1,4,5-trisphosphate receptor, type 3 |
| Other Description | IP3 receptor|inositol 1,4,5-triphosphate receptor, type 3|inositol 1,4,5-trisphosphate receptor type 3|insP3R3|type 3 InsP3 receptor |
| Swissprots | Q5TAQ2 Q14649 Q14573 |
| Accessions | CBX47635 EAX03744 Q14573 AB209739 BAD92976 AK093524 AL832807 BC041398 BC146646 AAI46647 BC172406 AAI72406 CA430212 D26351 BAA05385 U01062 AAC50064 XM_011514576 XP_011512878 XM_011514577 XP_011512879 NM_002224 NP_002215 |
| Function | Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. |
| Subcellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein. |
| Tissue Specificity | Expressed in intestinal crypt and villus epithelial cells. |
| Top Pathways | cGMP-PKG signaling pathway, Circadian entrainment, Glucagon signaling pathway, Estrogen signaling pathway, Thyroid hormone synthesis |