| Gene Symbol |
ITPR3
|
| Entrez Gene |
3710
|
| Alt Symbol |
IP3R, IP3R3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
inositol 1,4,5-trisphosphate receptor, type 3
|
| Other Description |
IP3 receptor|inositol 1,4,5-triphosphate receptor, type 3|inositol 1,4,5-trisphosphate receptor type 3|insP3R3|type 3 InsP3 receptor
|
| Swissprots |
Q5TAQ2 Q14649 Q14573
|
| Accessions |
CBX47635 EAX03744 Q14573 AB209739 BAD92976 AK093524 AL832807 BC041398 BC146646 AAI46647 BC172406 AAI72406 CA430212 D26351 BAA05385 U01062 AAC50064 XM_011514576 XP_011512878 XM_011514577 XP_011512879 NM_002224 NP_002215
|
| Function |
Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
|
| Subcellular Location |
Endoplasmic reticulum membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expressed in intestinal crypt and villus epithelial cells.
|
| Top Pathways |
cGMP-PKG signaling pathway, Circadian entrainment, Glucagon signaling pathway, Estrogen signaling pathway, Thyroid hormone synthesis
|