Gene Symbol | ITPR3 |
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Entrez Gene | 3710 |
Alt Symbol | IP3R, IP3R3 |
Species | Human |
Gene Type | protein-coding |
Description | inositol 1,4,5-trisphosphate receptor, type 3 |
Other Description | IP3 receptor|inositol 1,4,5-triphosphate receptor, type 3|inositol 1,4,5-trisphosphate receptor type 3|insP3R3|type 3 InsP3 receptor |
Swissprots | Q5TAQ2 Q14649 Q14573 |
Accessions | CBX47635 EAX03744 Q14573 AB209739 BAD92976 AK093524 AL832807 BC041398 BC146646 AAI46647 BC172406 AAI72406 CA430212 D26351 BAA05385 U01062 AAC50064 XM_011514576 XP_011512878 XM_011514577 XP_011512879 NM_002224 NP_002215 |
Function | Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. |
Subcellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in intestinal crypt and villus epithelial cells. |
Top Pathways | cGMP-PKG signaling pathway, Circadian entrainment, Glucagon signaling pathway, Estrogen signaling pathway, Thyroid hormone synthesis |
IP3R-III CRISPR/Cas9 KO Plasmid (h) - sc-402138 from Santa Cruz Biotechnology
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IP3R-III HDR Plasmid (h) - sc-402138-HDR from Santa Cruz Biotechnology
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IP3R-III Double Nickase Plasmid (h) - sc-402138-NIC from Santa Cruz Biotechnology
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IP3R-III Double Nickase Plasmid (h2) - sc-402138-NIC-2 from Santa Cruz Biotechnology
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IP3R-III CRISPR Activation Plasmid (h) - sc-402138-ACT from Santa Cruz Biotechnology
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IP3R-III CRISPR Activation Plasmid (h2) - sc-402138-ACT-2 from Santa Cruz Biotechnology
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IP3R-III Lentiviral Activation Particles (h) - sc-402138-LAC from Santa Cruz Biotechnology
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IP3R-III Lentiviral Activation Particles (h2) - sc-402138-LAC-2 from Santa Cruz Biotechnology
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IP3R-III siRNA (h) - sc-42477 from Santa Cruz Biotechnology
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IP3R-III shRNA Plasmid (h) - sc-42477-SH from Santa Cruz Biotechnology
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IP3R-III shRNA (h) Lentiviral Particles - sc-42477-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN2065 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2065 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06552 from Sigma-Aldrich
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ITPR3 siRNA (Human) - CRH2498 from Cohesion Biosciences
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IP3R3 RNAi - H00003710-R01 from Novus Biologicals
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ITPR3, siRNA - MBS8203001 from MyBioSource
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shRNA set against Human Itpr3 (NM_002224.3) - SHH321697 from Creative biogene
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Human ITPR3 siRNA - orb263000 from Biorbyt
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ITPR3 shRNA Plasmid (Human) - CHH2498 from Cohesion Biosciences
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ITPR3 miRNA 3'UTR clone - MiUTR3H-01194 from Creative biogene
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