| Gene Symbol |
PTDSS2
|
| Entrez Gene |
81490
|
| Alt Symbol |
PSS2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phosphatidylserine synthase 2
|
| Other Description |
PSS-2|ptdSer synthase 2|serine-exchange enzyme II
|
| Swissprots |
Q9BVG9
|
| Accessions |
EAX02327 EAX02328 EAX02329 Q9BVG9 AK307374 AK311723 AL834357 CAD39022 BC001210 AAH01210 BC015702 DQ891743 ABM82669 DQ894922 ABM85848 XM_005253153 XP_005253210 XM_011520391 XP_011518693 XM_011520392 XP_011518694 XM_011520393 XP_011518695 XR_242827 XR_242828 NM_030783 NP_110410
|
| Function |
Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. PTDSS2 is specific for phosphatatidylethanolamine and does not act on phosphatidylcholine.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Highly enriched in the mitochondria-associated membrane (MAM). {ECO:0000250}.
|
| Top Pathways |
Glycerophospholipid metabolism
|
![Western Blot: PTDSS2 Overexpression Lysate (Adult Normal) [NBP2-04397] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PTDSS2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4214_PTDSS2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-04397-img0001.jpg)