Gene Symbol | PTDSS2 |
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Entrez Gene | 81490 |
Alt Symbol | PSS2 |
Species | Human |
Gene Type | protein-coding |
Description | phosphatidylserine synthase 2 |
Other Description | PSS-2|ptdSer synthase 2|serine-exchange enzyme II |
Swissprots | Q9BVG9 |
Accessions | EAX02327 EAX02328 EAX02329 Q9BVG9 AK307374 AK311723 AL834357 CAD39022 BC001210 AAH01210 BC015702 DQ891743 ABM82669 DQ894922 ABM85848 XM_005253153 XP_005253210 XM_011520391 XP_011518693 XM_011520392 XP_011518694 XM_011520393 XP_011518695 XR_242827 XR_242828 NM_030783 NP_110410 |
Function | Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. PTDSS2 is specific for phosphatatidylethanolamine and does not act on phosphatidylcholine. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Highly enriched in the mitochondria-associated membrane (MAM). {ECO:0000250}. |
Top Pathways | Glycerophospholipid metabolism |
PSS2 CRISPR/Cas9 KO Plasmid (h) - sc-404133 from Santa Cruz Biotechnology
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PSS2 HDR Plasmid (h) - sc-404133-HDR from Santa Cruz Biotechnology
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PSS2 Double Nickase Plasmid (h) - sc-404133-NIC from Santa Cruz Biotechnology
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PSS2 Double Nickase Plasmid (h2) - sc-404133-NIC-2 from Santa Cruz Biotechnology
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PSS2 CRISPR Activation Plasmid (h) - sc-404133-ACT from Santa Cruz Biotechnology
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PSS2 CRISPR Activation Plasmid (h2) - sc-404133-ACT-2 from Santa Cruz Biotechnology
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PSS2 Lentiviral Activation Particles (h) - sc-404133-LAC from Santa Cruz Biotechnology
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PSS2 Lentiviral Activation Particles (h2) - sc-404133-LAC-2 from Santa Cruz Biotechnology
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PSS2 siRNA (h) - sc-72367 from Santa Cruz Biotechnology
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PSS2 shRNA Plasmid (h) - sc-72367-SH from Santa Cruz Biotechnology
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PSS2 shRNA (h) Lentiviral Particles - sc-72367-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN17661 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17661 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06447 from Sigma-Aldrich
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PTDSS2 siRNA (Human) - CRJ2974 from Cohesion Biosciences
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shRNA set against Human PTDSS2 (NM_030783.1) - SHH385896 from Creative biogene
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shRNA set against Human PTDSS2(NM_030783.1) - SHR150060 from Creative biogene
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Human PTDSS2 siRNA - orb273475 from Biorbyt
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PTDSS2 shRNA Plasmid (Human) - CHJ2974 from Cohesion Biosciences
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PTDSS2 miRNA 3'UTR clone - MiUTR1H-08411 from Creative biogene
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