Gene Symbol | UBAP1 |
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Entrez Gene | 51271 |
Alt Symbol | NAG20, UAP, UBAP, UBAP-1 |
Species | Human |
Gene Type | protein-coding |
Description | ubiquitin associated protein 1 |
Other Description | nasopharyngeal carcinoma-associated gene 20 protein|ubiquitin-associated protein 1 |
Swissprots | Q8NCH9 F5GXE2 Q6FI75 Q5T7B3 B7Z348 B7Z8N9 Q8NC52 F5H0J8 D3DRL7 Q4V759 Q9NZ09 Q53FP7 Q8NCG6 |
Accessions | CAF86203 CAF86817 EAW58467 EAW58468 EAW58469 EAW58470 Q9NZ09 AF222043 AAF37827 AK074426 AK074724 BAC11162 AK074745 BAC11176 AK074812 BAC11224 AK074969 BAC11323 AK074995 BAC11342 AK223235 BAD96955 AK295482 BAH12084 AK303711 BAH14025 AK309329 AL136733 CAB66667 AM393865 CAL38740 BC020950 AAH20950 BC098141 AAH98141 BC098316 AAH98316 BC099726 AAH99726 BC100668 AAI00669 BF527586 BP237024 BX473128 CR533551 CAG38582 DA741347 DQ891690 ABM82616 DQ894873 ABM85799 XM_006716779 XP_006716842 XM_011517898 XP_011516200 XM_011517899 XP_011516201 XM_011517900 XP_011516202 NM_001171201 NP_001164672 NM_001171202 NP_001164673 NM_001171203 NP_001164674 NM_001171204 NP_001164675 NM_016525 NP_057609 NR_033243 |
Function | Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Plays a role in the proteasomal degradation of ubiquitinated cell-surface proteins, such as EGFR and BST2. {ECO:0000269|PubMed:21757351, ECO:0000269|PubMed:22405001}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:21757351}. Endosome {ECO:0000269|PubMed:21757351}. Note=Predominantly cytosolic. Recruited to endosomes as part of the ESCRT-I complex. |
Tissue Specificity | Ubiquitous. Highly expressed in heart, brain, placenta, lung, liver, skeletal muscle and pancreas. {ECO:0000269|PubMed:11599797}. |
Human UBAP1 full length protein - ab162483 from Abcam
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Human UBAP1 full length protein - ab152036 from Abcam
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NAG20 / UBAP1 Antibody Blocking Peptide - LS-E9804 from LifeSpan Bioscience
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Recombinant Human UBAP1 Protein - H00051271-P01 from Novus Biologicals
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UBAP1-Antibody-N-term-Blocking-Peptide - BP8828a from Abgent, a WuXi AppTec company
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Human UBAP1 protein - orb49712 from Biorbyt
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UBAP1 / NAG20 - H00051271-P01-10 from Acris Antibodies
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UBAP1 / NAG20 - H00051271-P01-25 from Acris Antibodies
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Ubiquitin-associated protein 1, UBAP1, Human, Recombinant - 19-CE46 from ARP American Research Products
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UBAP1 fusion protein - Ag17675 from Proteintech Group
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UBAP1 fusion protein - Ag3055 from Proteintech Group
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Recombinant Human UBAP1 Protein - BP001378-CE46 from Syd Labs
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Recombinant Human UBAP1, His-tagged - UBAP1-3520H from Creative Biomart
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Recombinant Human Ubiquitin-associated protein 1(UBAP1) - CSB-YP873701HU CSB-EP873701HU CSB-BP873701HU CSB-MP873701HU from Cusabio
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Recombinant Ubiquitin Associated Protein 1 (UBAP1) - RPC583Hu01 from Uscn Life Science Inc.
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Recombinant Ubiquitin Associated Protein 1 (UBAP1) - RPC583Mu01 from Uscn Life Science Inc.
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UBAP1 / NAG20 - TP301858 from Acris Antibodies
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Recombinant Ubiquitin Associated Protein 1 (UBAP1) - RPC583Hu01 from Cloud-clone
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UBAP1 Recombinant Protein Antigen - NBP1-80651PEP from Novus Biologicals
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UBAP1 Peptide, Human - M34GP16938H from Creative Peptides
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UBAP1 Recombinant Protein (OPCD00728) - OPCD00728 from Aviva Systems Biology
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UBAP1 Recombinant Protein - 92-012 from ProSci
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Human UBAP1 protein - orb392649 from Biorbyt
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UBAP1 Recombinant Protein Antigen - NBP2-58969PEP from Novus Biologicals
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