| Gene Symbol |
ACSM1
|
| Entrez Gene |
116285
|
| Alt Symbol |
BUCS1, MACS1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
acyl-CoA synthetase medium-chain family member 1
|
| Other Description |
Butyrate CoA ligase|acyl-coenzyme A synthetase ACSM1, mitochondrial|butyrate--CoA ligase 1|butyryl Coenzyme A synthetase 1|butyryl-coenzyme A synthetase 1|lipoate-activating enzyme|medium-chain acyl-CoA synthetase|middle-chain acyl-CoA synthetase 1
|
| Swissprots |
Q08AH1 Q96A20 Q08AH2
|
| Accessions |
AAC23498 BAB68363 EAW66826 EAW66827 EAW66828 Q08AH1 AB059429 BAB64535 AK092574 AK314282 BAG36941 BC125177 AAI25178 BC125178 AAI25179 XM_005255084 XP_005255141 XM_006721016 XP_006721079 XM_006721017 XP_006721080 XM_006721018 XP_006721081 XM_011545729 XP_011544031 XM_011545730 XP_011544032 XM_011545731 XP_011544033 XM_011545732 XP_011544034 XR_243258 XR_429672 XR_950737 XR_950738 XR_950740 NM_052956 NP_443188
|
| Function |
Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4- unsaturated acids (in vitro). Functions as GTP-dependent lipoate- activating enzyme that generates the substrate for lipoyltransferase (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Mitochondrion matrix {ECO:0000250}.
|
| Top Pathways |
Butanoate metabolism
|