| Gene Symbol |
Apobec1
|
| Entrez Gene |
11810
|
| Alt Symbol |
Cdar1
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
|
| Other Description |
C->U-editing enzyme APOBEC-1|apolipoprotein B editing complex 1
|
| Swissprots |
Q99L67 P51908
|
| Accessions |
AAC52211 EDK99689 EDK99690 EDK99691 P51908 AK146427 BAE27161 AK151799 BAE30699 AK165209 BAE38079 AK166412 BAE38760 BC003792 AAH03792 BE634918 U22262 AAC52212 U22263 AAC52213 U22264 AAC52214 XM_006505401 XP_006505464 XM_011241159 XP_011239461 XM_011241160 XP_011239462 NM_031159 NP_112436 NM_001134391 NP_001127863
|
| Function |
Catalytic component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the APOB mRNA. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation. {ECO:0000269|PubMed:21496894}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}.
|
| Tissue Specificity |
Expressed in the spleen. Expressed at lower level in the kidney, testis, lung, brain and liver. {ECO:0000269|PubMed:12859895}.
|