Gene Symbol | Apobec1 |
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Entrez Gene | 11810 |
Alt Symbol | Cdar1 |
Species | Mouse |
Gene Type | protein-coding |
Description | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 |
Other Description | C->U-editing enzyme APOBEC-1|apolipoprotein B editing complex 1 |
Swissprots | Q99L67 P51908 |
Accessions | AAC52211 EDK99689 EDK99690 EDK99691 P51908 AK146427 BAE27161 AK151799 BAE30699 AK165209 BAE38079 AK166412 BAE38760 BC003792 AAH03792 BE634918 U22262 AAC52212 U22263 AAC52213 U22264 AAC52214 XM_006505401 XP_006505464 XM_011241159 XP_011239461 XM_011241160 XP_011239462 NM_031159 NP_112436 NM_001134391 NP_001127863 |
Function | Catalytic component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the APOB mRNA. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation. {ECO:0000269|PubMed:21496894}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Tissue Specificity | Expressed in the spleen. Expressed at lower level in the kidney, testis, lung, brain and liver. {ECO:0000269|PubMed:12859895}. |
APOBEC1 CRISPR/Cas9 KO Plasmid (m) - sc-419161 from Santa Cruz Biotechnology
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APOBEC1 HDR Plasmid (m) - sc-419161-HDR from Santa Cruz Biotechnology
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APOBEC1 Double Nickase Plasmid (m) - sc-419161-NIC from Santa Cruz Biotechnology
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APOBEC1 Double Nickase Plasmid (m2) - sc-419161-NIC-2 from Santa Cruz Biotechnology
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APOBEC1 CRISPR Activation Plasmid (m) - sc-419161-ACT from Santa Cruz Biotechnology
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APOBEC1 CRISPR Activation Plasmid (m2) - sc-419161-ACT-2 from Santa Cruz Biotechnology
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APOBEC1 Lentiviral Activation Particles (m) - sc-419161-LAC from Santa Cruz Biotechnology
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APOBEC1 Lentiviral Activation Particles (m2) - sc-419161-LAC-2 from Santa Cruz Biotechnology
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APOBEC1 siRNA (m) - sc-41183 from Santa Cruz Biotechnology
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Apobec1 shRNA Plasmid (m) - sc-41183-SH from Santa Cruz Biotechnology
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Apobec1 shRNA (m) Lentiviral Particles - sc-41183-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU010231 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN26841 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND26841 from Sigma-Aldrich
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APOBEC1 siRNA (Mouse) - CRM0218 from Cohesion Biosciences
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APOBEC1 - MBS8232069 from MyBioSource
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shRNA set against Mouse Apobec1 (NM_031159.3) - SHH238398 from Creative biogene
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shRNA set against Mouse Apobec1(NM_031159.3) - SHG065383 from Creative biogene
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Mouse APOBEC1 siRNA - orb279694 from Biorbyt
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APOBEC1 shRNA Plasmid (Mouse) - CHM0218 from Cohesion Biosciences
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APOBEC1 miRNA 3'UTR clone - MiUTR1M-01581 from Creative biogene
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