Gene Symbol | TIMP4 |
---|---|
Entrez Gene | 7079 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | TIMP metallopeptidase inhibitor 4 |
Other Description | TIMP-4|metalloproteinase inhibitor 4|tissue inhibitor of metalloproteinase 4|tissue inhibitor of metalloproteinases 4 |
Swissprots | Q99727 B2R7K6 |
Accessions | AAC34422 EAW64122 Q99727 AK313018 BAG35853 BC010553 AAH10553 BT019627 AAV38433 DQ891795 ABM82721 DQ894978 ABM85904 U76456 AAB40391 NM_003256 NP_003247 |
Function | Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP- 9. |
Subcellular Location | Secreted. |
Tissue Specificity | Abundant in heart and present at low levels in many other tissues. |