Gene Symbol | TIMP4 |
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Entrez Gene | 7079 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | TIMP metallopeptidase inhibitor 4 |
Other Description | TIMP-4|metalloproteinase inhibitor 4|tissue inhibitor of metalloproteinase 4|tissue inhibitor of metalloproteinases 4 |
Swissprots | Q99727 B2R7K6 |
Accessions | AAC34422 EAW64122 Q99727 AK313018 BAG35853 BC010553 AAH10553 BT019627 AAV38433 DQ891795 ABM82721 DQ894978 ABM85904 U76456 AAB40391 NM_003256 NP_003247 |
Function | Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP- 9. |
Subcellular Location | Secreted. |
Tissue Specificity | Abundant in heart and present at low levels in many other tissues. |
TIMP-4 CRISPR/Cas9 KO Plasmid (h) - sc-402560 from Santa Cruz Biotechnology
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TIMP-4 HDR Plasmid (h) - sc-402560-HDR from Santa Cruz Biotechnology
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TIMP-4 Double Nickase Plasmid (h) - sc-402560-NIC from Santa Cruz Biotechnology
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TIMP-4 Double Nickase Plasmid (h2) - sc-402560-NIC-2 from Santa Cruz Biotechnology
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TIMP-4 CRISPR Activation Plasmid (h) - sc-402560-ACT from Santa Cruz Biotechnology
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TIMP-4 CRISPR Activation Plasmid (h2) - sc-402560-ACT-2 from Santa Cruz Biotechnology
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TIMP-4 Lentiviral Activation Particles (h) - sc-402560-LAC from Santa Cruz Biotechnology
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TIMP-4 Lentiviral Activation Particles (h2) - sc-402560-LAC-2 from Santa Cruz Biotechnology
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TIMP-4 siRNA (h) - sc-36679 from Santa Cruz Biotechnology
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TIMP-4 shRNA Plasmid (h) - sc-36679-SH from Santa Cruz Biotechnology
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TIMP-4 shRNA (h) Lentiviral Particles - sc-36679-V from Santa Cruz Biotechnology
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TIMP-4 RNAi - H00007079-R01 from Novus Biologicals
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MISSION® esiRNA - EHU026461 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21370 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21370 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03870 from Sigma-Aldrich
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TIMP4 siRNA (Human) - CRH4848 from Cohesion Biosciences
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TIMP4 - MBS8205269 from MyBioSource
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TIMP-4 CRISPR/Cas9 KO Plasmid (h2) - sc-402560-KO-2 from Santa Cruz Biotechnology
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TIMP-4 HDR Plasmid (h2) - sc-402560-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human TIMP4 (NM_003256.3) - SHH427556 from Creative biogene
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Human TIMP4 siRNA - orb265350 from Biorbyt
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TIMP4 shRNA Plasmid (Human) - CHH4848 from Cohesion Biosciences
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TIMP4 miRNA 3'UTR clone - MiUTR3H-04499 from Creative biogene
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