SCEL

Gene Symbol SCEL
Entrez Gene 8796
Alt Symbol -
Species Human
Gene Type protein-coding
Description sciellin
Other Description -
Swissprots Q5W0S8 Q53H61 O95171 B7Z797 Q86X00 Q5W0S9 F5H651
Accessions EAW80568 EAW80569 O95171 AF045941 AAC78461 AK025320 AK222720 BAD96440 AK301659 BAH13533 BC020726 AAH20726 BC047536 AAH47536 BM973059 DC372982 JF432350 ADZ15567 XM_005266578 XP_005266635 XM_006719882 XP_006719945 XM_006719884 XP_006719947 XM_006719885 XP_006719948 XM_011535281 XP_011533583 XM_011535282 XP_011533584 XM_011535283 XP_011533585 XM_011535284 XP_011533586 XM_011535285 XP_011533587 XM_011535286 XP_011533588 XM_011535287 XP_011533589 XM_011535288 XP_011533590 XM_011535289 XP_011533591 XM_011535290 XP_011533592 XM_011535291 XP_011533593 NM_001160706 NP_001154178 NM_003843 NP_003834 NM_144777 NP_659001
Function May function in the assembly or regulation of proteins in the cornified envelope. The LIM domain may be involved in homotypic or heterotypic associations and may function to localize sciellin to the cornified envelope.
Subcellular Location Cytoplasm. Membrane. Note=May become cross- linked to membrane proteins by transglutaminase.
Tissue Specificity Highly expressed in esophagus. It is also expressed in keratinocytes, amniotic tissue, foreskin stratum spinosum and stratum granulosum, hair follicle and nail.

Sciellin (C-20) - sc-49316 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Sciellin (N-16) - sc-49318 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-SCEL antibody - ab170476 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Flow cytometric analysis of A549 cells labeling SCEL with ab170476 at 1/10 dilution (right histogram)  compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Anti-SCEL antibody - ab197087 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-SCEL antibody (ab197087) at 1/500 dilutionLane 1 : A549 lysateLane 2 : 7721 lysateLane 3 : B16 lysateLane 4 : SK-HEP-1 lysateLane 5 : SW620 lysate

Anti-SCEL antibody - ab69839 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-SCEL antibody (ab69839) at 1/500 dilutionLane 1 : SCEL transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-SCEL Antibody (aa260-289, APC) - LS-C240434 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SCEL Antibody (aa260-289, AP) - LS-C240436 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SCEL Antibody (aa260-289, Biotin) - LS-C240437 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SCEL Antibody (aa260-289, FITC) - LS-C240438 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SCEL Antibody (aa260-289, PE) - LS-C240441 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SCEL Antibody (aa260-289, Azide-free, HRP) - LS-C248088 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SCEL Antibody (aa247-277) - LS-C324932 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SCEL Antibody (aa540-589) - LS-C135247 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SCEL antibody LS-C135247 Western blot of Rat Heart lysate. Antibody concentration 1 ug/ml.

Anti-SCEL Antibody (aa260-289) - LS-C162892 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SCEL Antibody western blot of NCI-H292,A549 cell line lysates (35 ug/lane). The SCEL antibody detected the SCEL protein (arrow).

SCEL Antibody - NBP1-82138 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SCEL Antibody [NBP1-82138] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue. Lane 6: Human tonsil tissue

SCEL Antibody - NBP1-82137 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SCEL Antibody [NBP1-82137] - Analysis in human cell line RT-4, human cell line U-251 MG, human plasma, human liver tissue and human tonsil tissue.

SCEL Antibody - H00008796-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: SCEL Antibody [H00008796-B01P] - Analysis of SCEL expression in transfected 293T cell line by SCEL polyclonal antibody. Lane 1: SCEL transfected lysate(73.48 KDa). Lane 2: Non-transfected lysate.

SCEL Antibody (4B12) - H00008796-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4B12
Sandwich ELISA: SCEL Antibody (4B12) [H00008796-M01] - Detection limit for recombinant GST tagged SCEL is 0.1 ng/ml as a capture antibody.

SCEL Polyclonal Antibody - bs-7875R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SCEL antibody produced in rabbit - HPA039737 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SCEL: <B>Cat. No. HPA039737</B>: Immunohistochemical staining of human esophagus shows strong membranous and cytoplasmic positivity in superficial layers of squamous epithelial cells.

Anti-SCEL antibody produced in mouse - SAB1406726 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SCEL: <B>Cat. No. SAB1406726</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~73.5 kDa using SCEL transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Monoclonal Anti-SCEL antibody produced in mouse - SAB1403004 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4B12
<B>Immunoblotting</B><BR/>Monoclonal Anti-SCEL: <B>Cat. No. SAB1403004</B>: Antibody concentration: 1 μg/mL. Specific band of ~36.7 kDa using immunogen protein lysate.

Anti-SCEL antibody produced in rabbit - HPA040154 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SCEL: <B>Cat. No. HPA040154</B>: Immunohistochemical staining of human esophagus shows strong cytoplasmic and membranous positivity in squamous epithelial cells.

Anti-SCEL (201-215) antibody produced in rabbit - SAB1100782 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-SCEL (201-215) : <B>Cat. No. SAB1100782</B>: Immunofluorescence of HUVEC cells using SCEL (201-215) , Cat. No. SAB1100782 (red) at a 1:100 dilution, taken at 40x magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-SCEL (31-45) antibody produced in rabbit - SAB1100781 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-SCEL (31-45) : <B>Cat. No. SAB1100781</B>: Immunofluorescence of HUVEC cells using SCEL (31-45) , Cat. No. SAB1100781 (red) at a 1:50 dilution, taken at 40x magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com
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