Gene Symbol | SCEL |
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Entrez Gene | 8796 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | sciellin |
Other Description | - |
Swissprots | Q5W0S8 Q53H61 O95171 B7Z797 Q86X00 Q5W0S9 F5H651 |
Accessions | EAW80568 EAW80569 O95171 AF045941 AAC78461 AK025320 AK222720 BAD96440 AK301659 BAH13533 BC020726 AAH20726 BC047536 AAH47536 BM973059 DC372982 JF432350 ADZ15567 XM_005266578 XP_005266635 XM_006719882 XP_006719945 XM_006719884 XP_006719947 XM_006719885 XP_006719948 XM_011535281 XP_011533583 XM_011535282 XP_011533584 XM_011535283 XP_011533585 XM_011535284 XP_011533586 XM_011535285 XP_011533587 XM_011535286 XP_011533588 XM_011535287 XP_011533589 XM_011535288 XP_011533590 XM_011535289 XP_011533591 XM_011535290 XP_011533592 XM_011535291 XP_011533593 NM_001160706 NP_001154178 NM_003843 NP_003834 NM_144777 NP_659001 |
Function | May function in the assembly or regulation of proteins in the cornified envelope. The LIM domain may be involved in homotypic or heterotypic associations and may function to localize sciellin to the cornified envelope. |
Subcellular Location | Cytoplasm. Membrane. Note=May become cross- linked to membrane proteins by transglutaminase. |
Tissue Specificity | Highly expressed in esophagus. It is also expressed in keratinocytes, amniotic tissue, foreskin stratum spinosum and stratum granulosum, hair follicle and nail. |
Sciellin CRISPR/Cas9 KO Plasmid (h) - sc-411211 from Santa Cruz Biotechnology
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Sciellin HDR Plasmid (h) - sc-411211-HDR from Santa Cruz Biotechnology
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Sciellin Double Nickase Plasmid (h) - sc-411211-NIC from Santa Cruz Biotechnology
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Sciellin Double Nickase Plasmid (h2) - sc-411211-NIC-2 from Santa Cruz Biotechnology
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Sciellin CRISPR Activation Plasmid (h) - sc-411211-ACT from Santa Cruz Biotechnology
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Sciellin CRISPR Activation Plasmid (h2) - sc-411211-ACT-2 from Santa Cruz Biotechnology
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Sciellin Lentiviral Activation Particles (h) - sc-411211-LAC from Santa Cruz Biotechnology
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Sciellin Lentiviral Activation Particles (h2) - sc-411211-LAC-2 from Santa Cruz Biotechnology
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Sciellin siRNA (h) - sc-61501 from Santa Cruz Biotechnology
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Sciellin shRNA Plasmid (h) - sc-61501-SH from Santa Cruz Biotechnology
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Sciellin shRNA (h) Lentiviral Particles - sc-61501-V from Santa Cruz Biotechnology
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SCEL RNAi - H00008796-R02 from Novus Biologicals
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SCEL RNAi - H00008796-R01 from Novus Biologicals
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MISSION® esiRNA - EHU094301 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18924 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18924 from Sigma-Aldrich
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SCEL siRNA (Human) - CRH5796 from Cohesion Biosciences
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SCEL - MBS8221629 from MyBioSource
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shRNA set against Human SCEL (NM_003843.3) - SHH402508 from Creative biogene
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Human SCEL siRNA - orb266298 from Biorbyt
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SCEL shRNA Plasmid (Human) - CHH5796 from Cohesion Biosciences
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SCEL miRNA 3'UTR clone - MiUTR4H-TG07825 from Creative biogene
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