PYGL

Gene Symbol	PYGL
Entrez Gene	5836
Alt Symbol	GSD6
Species	Human
Gene Type	protein-coding
Description	phosphorylase, glycogen, liver
Other Description	glycogen phosphorylase, liver form
Swissprots	O60752 F5H816 Q501V9 B4DUB7 Q96G82 Q641R5 P06737 O60567 O60913 A6NDQ4
Accessions	AAC18079 EAW65685 EAW65686 EAW65687 P06737 AA523002 AF046785 AAC23504 AF066858 AAC17450 AK225904 AK300580 BAG62279 AK309333 AK313206 BAG36022 AL134906 AY429567 BC009895 AAH09895 BC065011 AAH65011 BC082229 AAH82229 BC095850 AAH95850 BC110791 AAI10792 DA287767 M14636 AAA52577 M36807 AAA35906 Y15233 CAA75517 NM_001163940 NP_001157412 NM_002863 NP_002854
Function	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
Top Pathways	Insulin signaling pathway, Glucagon signaling pathway, Starch and sucrose metabolism

PYGB/L/M (H-300) - sc-66913 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

PYGB/L/M (H-300): sc-66913. Immunoperoxidase staining of formalin fixed, paraffin-embedded human liver tissue showing cytoplasmic staining of hepatocytes and bile duct cells.

PYGB/L/M (N-20) - sc-46347 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

PYGB/L/M (N-20): sc-46347. Western blot analysis of PYGB expression in c4 (A), EOC 20 (B) and Sol8 (C) whole cell lysates.

Anti-PYGL antibody - ab198268 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-PYGL antibody (ab198268) at 1/400 dilutionLane 1 : 231 cell lysateLane 2 : PC3 cell lysateLysates/proteins at 40 µg per lane.developed using the ECL technique

Anti-PYGL antibody - ab103419 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PYGL antibody (ab103419) at 5 µg/ml + Human liver tissue lysate at 50 µg

Anti-PYGL antibody - ab61013 from Abcam

Prices	$407.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

ab61013 at 10µg/ml staining formalin fixed paraffin embedded liver tissue.

Anti-PYGL antibody - C-terminal - ab190243 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-PYGL antibody - C-terminal (ab190243) at 0.1 µg/mlLane 1 : HeLa whole cell lysateLane 2 : 293T whole cell lysateLane 3 : Jurkat whole cell lysateLane 4 : TCMK-1 whole cell lysateLane 5 : NIH 3T3 whole cell lysateLysates/proteins at 50 µg per lane.developed using the ECL technique

Anti-PYGL antibody - C-terminal - ab150307 from Abcam

Prices	$407.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Immunohistochemical analysis of formalin fixed, paraffin embedded Human liver tissue labelling PYGL with ab150307 at 10 ug/ml, (after heat-induced antigen retrieval).

Anti-PYGL Antibody - LS-C152971 from LifeSpan Bioscience

Prices	$475.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PYGL Antibody - LS-C285592 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-PYGL Antibody (aa370-538, Biotin) - LS-C297234 from LifeSpan Bioscience

Prices	$405.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PYGL Antibody (aa633-820, Biotin) - LS-C297429 from LifeSpan Bioscience

Prices	$405.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PYGL Antibody (aa341-509, Biotin) - LS-C297432 from LifeSpan Bioscience

Prices	$425.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PYGL Antibody (aa633-820) - LS-C294283 from LifeSpan Bioscience

Prices	$385.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PYGL Antibody (aa341-509) - LS-C294284 from LifeSpan Bioscience

Prices	$395.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PYGL Antibody (aa603-750, Biotin) - LS-C300148 from LifeSpan Bioscience

Prices	$425.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PYGL Antibody (aa633-820, FITC) - LS-C301791 from LifeSpan Bioscience

Prices	$425.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PYGL Antibody (aa341-509, FITC) - LS-C301792 from LifeSpan Bioscience

Prices	$445.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PYGL Antibody (aa370-538) - LS-C294286 from LifeSpan Bioscience

Prices	$385.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PYGL Antibody (aa603-750) - LS-C294287 from LifeSpan Bioscience

Prices	$395.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PYGL Antibody (aa370-538, FITC) - LS-C304057 from LifeSpan Bioscience

Prices	$425.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PYGL Antibody (aa603-750, FITC) - LS-C304762 from LifeSpan Bioscience

Prices	$445.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PYGL Antibody (Biotin) - LS-C317222 from LifeSpan Bioscience

Prices	$305.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PYGL Antibody (HRP) - LS-C317223 from LifeSpan Bioscience

Prices	$305.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PYGL Antibody (FITC) - LS-C318841 from LifeSpan Bioscience

Prices	$305.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PYGL Antibody (aa797-847) - LS-C291000 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Detection of Human PYGL by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) prepared using RIPA buffer from 293T cells. Antibodies: Affinity purified rabbit anti-PYGL antibody used for IP at 6 ug per reaction. PYGL was also immunoprecipitated by rabbit anti-PYGL antibody BL15846. For blotting immunoprecipitated PYGL, was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

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