SPR

Gene Symbol SPR
Entrez Gene 6697
Alt Symbol SDR38C1
Species Human
Gene Type protein-coding
Description sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
Other Description sepiapterin reductase|short chain dehydrogenase/reductase family 38C, member 1
Swissprots D6W5H2 A8K741 P35270 Q53GI9 Q9UBB1
Accessions AAY14743 AAY15035 BAA34534 BAA34535 EAW99757 EAW99758 P35270 AK222942 BAD96662 AK291856 BAF84545 BC017310 AAH17310 BF434649 DQ891699 ABM82625 DQ894880 ABM85806 M76231 AAA60314 S71376 AAD14079 NM_003124 NP_003115
Function Catalyzes the final one or two reductions in tetra- hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin.
Subcellular Location Cytoplasm.
Top Pathways Folate biosynthesis

SPR (H-12) - sc-398126 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SPR (H-12): sc-398126. Western blot analysis of SPR expression in non-transfected: sc-117752 (A) and mouse SPR transfected: sc-123752 (B) 293T whole cell lysates.

SPR (G-14) - sc-169414 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SPR (G-14): sc-169414. Western blot analysis of SPR expression in non-transfected: sc-117752 (A) and mouse SPR transfected: sc-123752 (B) 293T whole cell lysates.

Anti-SPR antibody - ab103353 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-SPR antibody (ab103353) at 1/100 dilution + Mouse liver tissue lysate at 35 µg

Anti-SPR antibody - ab96027 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-SPR antibody (ab96027) at 1/1000 dilution + A431 whole cell lysate at 30 µg

Anti-SPR antibody [2C6] - ab119402 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2C6
All lanes : Anti-SPR antibody [2C6] (ab119402) at 1/500 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control cDNALane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY SPR cDNALysates/proteins at 5 µg per lane.developed using the ECL technique

Anti-SPR antibody [2F7] - ab117896 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2F7
All lanes : Anti-SPR antibody [2F7] (ab117896) at 1/500 dilutionLane 1 : HEK293T cells transfected with pCMV6-ENTRY control Lane 2 : HEK293T cells transfected with pCMV6-ENTRY SPRLysates/proteins at 5 µg per lane.

Anti-SPR antibody [EPR9289] - ab139185 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9289

Anti-SPR antibody [EPR9290] - ab157194 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9290
ab157194 showing +ve staining in Human normal pancreas.

Anti-SPR antibody - C-terminal - ab198716 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded human breast cancer tissue labeling SPR with ab198716 at 1/40 dilution.

Anti-SPR Antibody (aa231-260, AP) - LS-C270250 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SPR Antibody (aa231-260, APC) - LS-C270251 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SPR Antibody (aa231-260, Biotin) - LS-C270252 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SPR Antibody (aa231-260, FITC) - LS-C270253 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SPR Antibody (aa231-260, Azide-free, HRP) - LS-C270254 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SPR Antibody (aa231-260, PE) - LS-C270255 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SPR Antibody (aa232-261) - LS-C325347 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SPR Antibody (C-Terminus) - LS-C135571 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SPR antibody LS-C135571 Western blot of HeLa lysate.

Anti-SPR Antibody (aa231-260) - LS-C161469 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of SPR Antibody in mouse liver tissue lysates (35 ug/lane). SPR (arrow) was detected using the purified antibody.

Anti-SPR Antibody (clone 3C8) - LS-C337147 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3C8
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SPR (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SPR.

Anti-SPR Antibody (aa65-261) - LS-C186315 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescence of methanol-fixed HeLa using SPR antibody at 1:200 dilution.

Anti-SPR Antibody (clone 2F7) - LS-C115799 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2F7
Western blot of extracts (35 ug) from 9 different cell lines by using anti-SPR monoclonal antibody.

Anti-SPR Antibody (clone 4F2) - LS-C198255 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4F2
Western Blot analysis of SPR expression in transfected 293T cell line by SPR monoclonal antibody (M01), clone 4F2.Lane 1: SPR transfected lysate(28 KDa).Lane 2: Non-transfected lysate.

Anti-SPR Antibody (aa139-170) - LS-C344356 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysates from A431, A549, MCF-7 cell line (from left to right) with SPR Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35 ug per lane.

Anti-SPR Antibody (clone 3E3) - LS-C115811 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3E3
Anti-SPR mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SPR.

Anti-SPR Antibody (clone 2C6) - LS-C172431 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2C6
IHC of paraffin-embedded Carcinoma of Human pancreas tissue using anti-SPR mouse monoclonal antibody.
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