Gene Symbol | SPR |
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Entrez Gene | 6697 |
Alt Symbol | SDR38C1 |
Species | Human |
Gene Type | protein-coding |
Description | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
Other Description | sepiapterin reductase|short chain dehydrogenase/reductase family 38C, member 1 |
Swissprots | D6W5H2 A8K741 P35270 Q53GI9 Q9UBB1 |
Accessions | AAY14743 AAY15035 BAA34534 BAA34535 EAW99757 EAW99758 P35270 AK222942 BAD96662 AK291856 BAF84545 BC017310 AAH17310 BF434649 DQ891699 ABM82625 DQ894880 ABM85806 M76231 AAA60314 S71376 AAD14079 NM_003124 NP_003115 |
Function | Catalyzes the final one or two reductions in tetra- hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin. |
Subcellular Location | Cytoplasm. |
Top Pathways | Folate biosynthesis |
SPR CRISPR/Cas9 KO Plasmid (h) - sc-407926 from Santa Cruz Biotechnology
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SPR HDR Plasmid (h) - sc-407926-HDR from Santa Cruz Biotechnology
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SPR Double Nickase Plasmid (h) - sc-407926-NIC from Santa Cruz Biotechnology
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SPR Double Nickase Plasmid (h2) - sc-407926-NIC-2 from Santa Cruz Biotechnology
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SPR CRISPR Activation Plasmid (h) - sc-407926-ACT from Santa Cruz Biotechnology
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SPR CRISPR Activation Plasmid (h2) - sc-407926-ACT-2 from Santa Cruz Biotechnology
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SPR Lentiviral Activation Particles (h) - sc-407926-LAC from Santa Cruz Biotechnology
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SPR Lentiviral Activation Particles (h2) - sc-407926-LAC-2 from Santa Cruz Biotechnology
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SPR siRNA (h) - sc-94595 from Santa Cruz Biotechnology
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SPR shRNA Plasmid (h) - sc-94595-SH from Santa Cruz Biotechnology
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SPR shRNA (h) Lentiviral Particles - sc-94595-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU012911 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2138 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2138 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05592 from Sigma-Aldrich
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SPR siRNA (Human) - CRH4567 from Cohesion Biosciences
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SPR RNAi - H00006697-R01 from Novus Biologicals
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SPR - MBS8214874 from MyBioSource
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shRNA set against Human SPR (NM_003124.4) - SHH417164 from Creative biogene
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SPR shRNA Plasmid (Human) - CHH4567 from Cohesion Biosciences
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SPR miRNA 3'UTR clone - MiUTR3H-02088 from Creative biogene
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