Gene Symbol |
DUSP8
|
Entrez Gene |
1850
|
Alt Symbol |
C11orf81, HB5, HVH-5, HVH8
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
dual specificity phosphatase 8
|
Other Description |
H1 phosphatase, vaccinia virus homolog|dual specificity protein phosphatase 8|dual specificity protein phosphatase hVH-5|serine/threonine specific protein phosphatase
|
Swissprots |
Q86SS8 Q13202
|
Accessions |
EAX02451 EAX02452 Q13202 AK124467 BAC85857 AK124948 BAC86004 BC038231 AAH38231 BC045110 AAH45110 BU740880 U27193 AAA83151 XM_011519932 XP_011518234 XM_011519933 XP_011518235 XM_011519934 XP_011518236 XM_011546582 XP_011544884 XM_011546583 XP_011544885 XM_011546584 XP_011544886 XM_011547377 XP_011545679 XM_011547378 XP_011545680 XM_011547379 XP_011545681 NM_004420 NP_004411
|
Function |
This protein shows both activity toward tyrosine-protein phosphate as well as with serine/threonine-protein phosphate. {ECO:0000250}.
|
Subcellular Location |
Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
|
Tissue Specificity |
Abundant in brain, heart and skeletal muscle. {ECO:0000269|PubMed:7561881}.
|
Top Pathways |
MAPK signaling pathway
|