Gene Symbol | DUSP8 |
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Entrez Gene | 1850 |
Alt Symbol | C11orf81, HB5, HVH-5, HVH8 |
Species | Human |
Gene Type | protein-coding |
Description | dual specificity phosphatase 8 |
Other Description | H1 phosphatase, vaccinia virus homolog|dual specificity protein phosphatase 8|dual specificity protein phosphatase hVH-5|serine/threonine specific protein phosphatase |
Swissprots | Q86SS8 Q13202 |
Accessions | EAX02451 EAX02452 Q13202 AK124467 BAC85857 AK124948 BAC86004 BC038231 AAH38231 BC045110 AAH45110 BU740880 U27193 AAA83151 XM_011519932 XP_011518234 XM_011519933 XP_011518235 XM_011519934 XP_011518236 XM_011546582 XP_011544884 XM_011546583 XP_011544885 XM_011546584 XP_011544886 XM_011547377 XP_011545679 XM_011547378 XP_011545680 XM_011547379 XP_011545681 NM_004420 NP_004411 |
Function | This protein shows both activity toward tyrosine-protein phosphate as well as with serine/threonine-protein phosphate. {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
Tissue Specificity | Abundant in brain, heart and skeletal muscle. {ECO:0000269|PubMed:7561881}. |
Top Pathways | MAPK signaling pathway |
DUSP8 CRISPR/Cas9 KO Plasmid (h) - sc-404385 from Santa Cruz Biotechnology
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DUSP8 HDR Plasmid (h) - sc-404385-HDR from Santa Cruz Biotechnology
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DUSP8 Double Nickase Plasmid (h) - sc-404385-NIC from Santa Cruz Biotechnology
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DUSP8 Double Nickase Plasmid (h2) - sc-404385-NIC-2 from Santa Cruz Biotechnology
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DUSP8 CRISPR Activation Plasmid (h) - sc-404385-ACT from Santa Cruz Biotechnology
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DUSP8 CRISPR Activation Plasmid (h2) - sc-404385-ACT-2 from Santa Cruz Biotechnology
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DUSP8 Lentiviral Activation Particles (h) - sc-404385-LAC from Santa Cruz Biotechnology
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DUSP8 Lentiviral Activation Particles (h2) - sc-404385-LAC-2 from Santa Cruz Biotechnology
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DUSP8 siRNA (h) - sc-60556 from Santa Cruz Biotechnology
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DUSP8 shRNA Plasmid (h) - sc-60556-SH from Santa Cruz Biotechnology
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DUSP8 shRNA (h) Lentiviral Particles - sc-60556-V from Santa Cruz Biotechnology
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DUSP8 RNAi - H00001850-R01 from Novus Biologicals
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MISSION® esiRNA - EHU118201 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0150 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0148 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0149 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7561 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7561 from Sigma-Aldrich
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DUSP8 siRNA (Human) - CRH1298 from Cohesion Biosciences
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DUSP8 - MBS8214136 from MyBioSource
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Human DUSP8 siRNA - orb261800 from Biorbyt
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DUSP8 shRNA Plasmid (Human) - CHH1298 from Cohesion Biosciences
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