| Gene Symbol |
RXFP3
|
| Entrez Gene |
51289
|
| Alt Symbol |
GPCR135, RLN3R1, RXFPR3, SALPR
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
relaxin/insulin-like family peptide receptor 3
|
| Other Description |
G-protein coupled receptor GPCR135|G-protein coupled receptor SALPR|RLN3 receptor 1|g protein-coupled receptor SALPR|relaxin 3 receptor 1|relaxin family peptide receptor 3|relaxin-3 receptor 1|somatostatin and angiotensin-like peptide receptor|somatostatin- and angiotensin-like peptide receptor
|
| Swissprots |
Q14DA5 Q9NSD7
|
| Accessions |
AAO92063 EAX10810 Q9NSD7 AY394501 AAQ92315 BC095526 AAH95526 BC113438 AAI13439 BC113440 AAI13441 D88437 BAA93001 EU831822 ACE87340 EU831899 ACE86658 HQ258443 ADR83197 NM_016568 NP_057652
|
| Function |
Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation. {ECO:0000269|PubMed:14522968}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis.
|
![Western Blot: SALPR Overexpression Lysate (Adult Normal) [NBP2-04358] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SALPR.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8746_SALPR%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-04358-img0001.jpg)