Gene Symbol | RXFP3 |
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Entrez Gene | 51289 |
Alt Symbol | GPCR135, RLN3R1, RXFPR3, SALPR |
Species | Human |
Gene Type | protein-coding |
Description | relaxin/insulin-like family peptide receptor 3 |
Other Description | G-protein coupled receptor GPCR135|G-protein coupled receptor SALPR|RLN3 receptor 1|g protein-coupled receptor SALPR|relaxin 3 receptor 1|relaxin family peptide receptor 3|relaxin-3 receptor 1|somatostatin and angiotensin-like peptide receptor|somatostatin- and angiotensin-like peptide receptor |
Swissprots | Q14DA5 Q9NSD7 |
Accessions | AAO92063 EAX10810 Q9NSD7 AY394501 AAQ92315 BC095526 AAH95526 BC113438 AAI13439 BC113440 AAI13441 D88437 BAA93001 EU831822 ACE87340 EU831899 ACE86658 HQ258443 ADR83197 NM_016568 NP_057652 |
Function | Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation. {ECO:0000269|PubMed:14522968}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis. |
Relaxin Receptor 3 CRISPR/Cas9 KO Plasmid (h) - sc-407213 from Santa Cruz Biotechnology
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Relaxin Receptor 3 HDR Plasmid (h) - sc-407213-HDR from Santa Cruz Biotechnology
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Relaxin Receptor 3 Double Nickase Plasmid (h) - sc-407213-NIC from Santa Cruz Biotechnology
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Relaxin Receptor 3 Double Nickase Plasmid (h2) - sc-407213-NIC-2 from Santa Cruz Biotechnology
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Relaxin Receptor 3 CRISPR Activation Plasmid (h) - sc-407213-ACT from Santa Cruz Biotechnology
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Relaxin Receptor 3 CRISPR Activation Plasmid (h2) - sc-407213-ACT-2 from Santa Cruz Biotechnology
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Relaxin Receptor 3 Lentiviral Activation Particles (h) - sc-407213-LAC from Santa Cruz Biotechnology
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Relaxin Receptor 3 Lentiviral Activation Particles (h2) - sc-407213-LAC-2 from Santa Cruz Biotechnology
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Relaxin Receptor 3 siRNA (h) - sc-60717 from Santa Cruz Biotechnology
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Relaxin Receptor 3 shRNA Plasmid (h) - sc-60717-SH from Santa Cruz Biotechnology
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Relaxin Receptor 3 shRNA (h) Lentiviral Particles - sc-60717-V from Santa Cruz Biotechnology
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RXFP3/RLN3R1/SALPR RNAi - H00051289-R02 from Novus Biologicals
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MISSION® esiRNA - EHU136681 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18771 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18771 from Sigma-Aldrich
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RXFP3 siRNA (Human) - CRH9666 from Cohesion Biosciences
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RXFP3 - MBS8233643 from MyBioSource
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shRNA set against Human RXFP3 (NM_016568.3) - SHH400952 from Creative biogene
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Human RXFP3 siRNA - orb270168 from Biorbyt
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RXFP3 shRNA Plasmid (Human) - CHH9666 from Cohesion Biosciences
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RXFP3 miRNA 3'UTR clone - MiUTR4H-TG07742 from Creative biogene
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