Gene Symbol | OAZ1 |
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Entrez Gene | 4946 |
Alt Symbol | AZI, OAZ |
Species | Human |
Gene Type | protein-coding |
Description | ornithine decarboxylase antizyme 1 |
Other Description | ODC-Az|antizyme 1 |
Swissprots | Q9UPL9 Q92595 Q14989 O43382 P54368 |
Accessions | AAC02802 AAC02803 AAW56074 BAA23101 EAW69393 EAW69394 EAW69395 P54368 AF090094 AK307221 AL542477 BC007247 BC010063 BC013037 BC035151 BC042364 BC053360 BC055397 BC081537 BC093652 AAH93652 BC100291 BC112133 AAI12134 BI667301 BM423450 D78361 BAA11373 D87914 BAA13497 HY050868 U09202 AAA82154 NM_001301020 NP_001287949 NM_004152 NP_004143 |
Function | Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake by binding to and targeting ODC1 for degradation (PubMed:17900240). Stabilizes AZIN2 by interfering with its ubiquitination. Also inhibits cellular uptake of polyamines by inactivating the polyamine uptake transporter. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. Involved in the translocation of AZNI2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol. {ECO:0000269|PubMed:12097147, ECO:0000269|PubMed:17900240}. |
Human OAZ1 full length protein - ab131694 from Abcam
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OAZ1 / OAZ Antibody Blocking Peptide - LS-E8995 from LifeSpan Bioscience
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Recombinant Human OAZ1 Protein - NBP2-23310 from Novus Biologicals
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OAZ1-Antibody-N-term-Blocking-Peptide - BP7477a from Abgent, a WuXi AppTec company
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Human OAZ1 protein - orb168965 from Biorbyt
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OAZ1 protein (His tag) - 80R-2438 from Fitzgerald
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OAZ1 (1-228, His-tag) - AR50518PU-N from Acris Antibodies
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OAZ1 (1-228, His-tag) - AR50518PU-S from Acris Antibodies
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OAZ1 - P5863 from Acris Antibodies
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OAZ1, 1-228aa, Human, His tag, E.coli - 01-P1694 from ARP American Research Products
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OAZ1 fusion protein - ag13027 from Proteintech Group
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OAZ1 Human - PRPS-1207 from NeoScientific
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Recombinant Human OBFC1 Protein - BP002636-CF99 from Syd Labs
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OAZ1, 1-228aa, Recombinant Protein - GWB-P0344F from Genway Biotech
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Recombinant Human OAZ1 - OAZ1-543H from Creative Biomart
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Recombinant Ornithine Decarboxylase Antizyme 1 (OAZ1) - RPC685Hu01 from Uscn Life Science Inc.
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OAZ1 - PAT-80584-2 from Nordic BioSite
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OAZ1 - PAT-80584-1 from Nordic BioSite
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OAZ1 Blocking Peptide - CBP4137 from Cohesion Biosciences
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Recombinant Human Ornithine decarboxylase antizyme 1(OAZ1) - CSB-YP016245HU CSB-EP016245HU CSB-BP016245HU CSB-MP016245HU from Cusabio
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OAZ1, 1-228aa, Human, His tag, E.coli - ATGP1694 from ATGen
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OAZ1 Protein - abx164356 from Abbexa
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Ornithine Decarboxylase Antizyme 1 Protein (Recombinant) - abx262539 from Abbexa
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OAZ1 Recombinant Protein Antigen - NBP1-88925PEP from Novus Biologicals
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OAZ1 Blocking Peptide - abx162630 from Abbexa
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