| Gene Symbol |
TPSAB1
|
| Entrez Gene |
7177
|
| Alt Symbol |
TPS1, TPS2, TPSB1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tryptase alpha/beta 1
|
| Other Description |
mast cell alpha II tryptase|mast cell beta I tryptase|tryptase I|tryptase alpha II|tryptase alpha-1|tryptase alpha/beta-1|tryptase beta 1|tryptase beta I|tryptase beta-1|tryptase-1|tryptase-I|tryptase-III
|
| Swissprots |
Q15664 D2E6S0 Q9UQI1 Q9H2Y4 Q6B052 Q15661 Q9UQI7 P20231 O95827 Q9UQI6 D2E6S1 Q15663 P15157 D2E6S2 D2E6R9 Q9H2Y5
|
| Accessions |
AAC83172 AAD17846 AAD17860 AAK61271 ACZ98911 Q15661 AF206665 AAG35695 AF206666 AAG35696 AF206667 AAG35697 BC028059 AAH28059 BC038416 BC051852 AAH51852 BC074974 AAH74974 BC074975 AAH74975 CR541836 CAG46635 FJ931118 ACZ98912 M30038 AAA86934 M33491 AAA36778 NM_003294 NP_003285
|
| Function |
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. Has an immunoprotective role during bacterial infection. Required to efficiently combat K.pneumoniae infection (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Secreted. Note=Released from the secretory granules upon mast cell activation.
|
![Western Blot: Mast Cell Tryptase Overexpression Lysate (Native) [NBP2-08022] - Mast Cell Tryptase Overexpression Lysate (Native) Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TPSAB1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/24463_Mast-Cell-Tryptase-Overexpression-Lysate-%2528Native%2529-Western-Blot-NBP2-08022-img0002.jpg)