THRB

Gene Symbol THRB
Entrez Gene 7068
Alt Symbol C-ERBA-2, C-ERBA-BETA, ERBA2, GRTH, NR1A2, PRTH, THR1, THRB1, THRB2
Species Human
Gene Type protein-coding
Description thyroid hormone receptor, beta
Other Description nuclear receptor subfamily 1 group A member 2|oncogene ERBA2|thyroid hormone nuclear receptor beta variant 1|thyroid hormone receptor beta|thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
Swissprots B3KU79 P10828 Q9UD41 Q3KP35 P37243 Q6WGL2 Q13986
Accessions AAD49560 AAP32229 BAO48099 EAW64345 EAW64346 EAW64347 EAW64348 EAW64349 EAW64350 P10828 AB307687 BAH02278 AI003028 AK095776 AK096628 BAG53341 AK096885 AK098084 AK124042 AV747599 AW449568 AY286465 AAQ23704 AY286466 AAQ23705 AY286467 AAQ23706 AY286468 AAQ23707 AY286469 AAQ23708 AY286470 AAQ23709 AY286471 AAQ23710 BC028910 BC106929 AAI06930 BC106930 AAI06931 BF854291 BP313943 BQ879477 BX489919 DA218319 EU446664 ABZ92193 GQ456948 GQ456949 GQ456950 GQ456951 GQ869477 GQ869478 GQ869479 GQ919288 ADK27482 HQ692825 ADZ17336 M26747 AAA35677 X04707 CAA28412 X74497 CAA52606 XM_005265421 XP_005265478 XM_005265423 XP_005265480 XM_005265424 XP_005265481 XM_006713317 XP_006713380 XM_006713318 XP_006713381 XM_011534046 XP_011532348 XM_011534047 XP_011532349 XM_011534048 XP_011532350 XM_011534049 XP_011532351 XM_011534050 XP_011532352 XM_011534051 XP_011532353 XM_011534052 XP_011532354 XM_011534053 XP_011532355 NM_000461 NP_000452 NM_001128176 NP_001121648 NM_001128177 NP_001121649 NM_001252634 NP_001239563
Function Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine. {ECO:0000269|PubMed:12699376, ECO:0000269|PubMed:14673100, ECO:0000269|PubMed:16781732, ECO:0000269|PubMed:17418816, ECO:0000269|PubMed:18237438, ECO:0000269|PubMed:18798561, ECO:0000269|PubMed:19926848}.
Subcellular Location Nucleus.
Top Pathways Neuroactive ligand-receptor interaction

TRα1/β1 (C3) - sc-32754 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TRα1/β1 (C3): sc-32754. Western blot analysis of in vitro synthesized human TRβ1 (A-C) and TRα1 (D-F) prepared from TNT T7 programmed lysates. [1µL (A,D), 3µL (B,E), and 6µL (C,F)]

TRβ1 (E-17) - sc-34132 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TRβ1 (E-17): sc-34132. Western blot analysis of TRβ expression in non-transfected: sc-117752 (A) and human TRβ transfected: sc-369818 (B) 293T whole cell lysates.

TRβ1 (J51) - sc-737 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TRβ1 (J51): sc-737. Western blot analysis of TRβ1 expression in SK-BR-3 nuclear extract.

TRβ1 (J52) - sc-738 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TRβ1 (J52): sc-738. Western blot analysis of TRβ1 expression in C32 whole cell lysate.

TRβ1 (J53) - sc-56872 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TRβ1 (J53): sc-56872. Western blot analysis of TRβ1 expression in HTori cells transfected with TRβ1-pcDNA3.1 expression vector.

TRβ1 (N-12) - sc-33312 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TRβ1 (N-19) - sc-10822 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TRβ1 (N-19): sc-10822. Western blot analysis of TRβ1 expression in SK-BR-3 nuclear extract.

TRβ1 (P-16) - sc-10823 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TRβ1 (S-18) - sc-33313 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TRβ2 (H-110) - sc-67123 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

TRβ2 (L-20) - sc-34135 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TRβ2 (N-14) - sc-34138 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TRβ2 (N-16) - sc-10824 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TRβ2 (N-16): sc-10824. Immunoperoxidase staining of formalin fixed, paraffin-embedded human thyroid gland tissue showing cytoplasmic and nuclear staining of glandular cells.

TRβ2 (T-15) - sc-34137 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Thyroid Hormone Receptor beta (phospho S142) antibody - ab78913 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Thyroid Hormone Receptor beta (phospho S142) antibody (ab78913) at 1/500 dilutionLane 1 : 293 cell extracts, treated with PMA (125ng/ml, 30mins)Lane 2 : 293 cell extracts, treated with PMA (125ng/ml, 30mins) with immunising phosphopeptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-Thyroid Hormone Receptor beta 1 antibody - ab155297 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Thyroid Hormone Receptor beta 1 antibody (ab155297) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

Anti-Thyroid Hormone Receptor beta 1 antibody - N-terminal - ab180612 from Abcam

Prices $357.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Thyroid Hormone Receptor beta 1 antibody - N-terminal (ab180612) at 1/500 dilutionLane 1 : K562 cell extractLane 2 : PC3 cell extractLane 3 : HepG2 cell extractLane 4 : U251 cell extractLane 5 : Mouse liver extractLane 6 : Mouse cranio facial extract

Anti-Thyroid Hormone Receptor beta antibody - ab53170 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Thyroid Hormone Receptor beta antibody (ab53170) at 1/500 dilutionLane 1 : LoVo cell extracts minus immunising peptideLane 2 : LoVo cell extracts plus immunising peptide

Anti-Thyroid Hormone Receptor beta antibody [J52] - ab2744 from Abcam

Prices $379.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone J52

Anti-Thyroid Hormone Receptor beta antibody - ChIP Grade - ab5622 from Abcam

Prices $381.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab5622 labelling Thyroid Hormaone Receptor beta in the nucleus of Rat thyroid tissue (right) compared with a negative control (left). To expose target proteins, antigen retrieval method was performed using 10mM sodium citrate (pH 6.0) microwaved for 8-15 min. Following antigen retrieval, tissues were blocked in 3% H2O2-methanol for 15 min at room temperature. Tissue sections were incubated with the primary antibody (1:200 in 3% BSA-PBS) overnight at 4°C. A HRP-conjugated anti-rabbit IgG was used as the secondary antibody, followed by colorimetric detection using a DAB kit. Tissues were counterstained with hematoxylin and dehydrated with ethanol and xylene to prep for mounting.

Anti-Thyroid Hormone Receptor beta antibody - N-terminal - ab196484 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Thyroid Hormone Receptor beta antibody - N-terminal (ab196484) at 1/500 dilutionLane 1 : K562 cell extractLane 2 : PC3 cell extractLane 3 : HepG2 cell extractLane 4 : U251 cell extractLane 5 : Mouse liver tissue extractLane 6 : Mouse craniofacial tissue extract

Anti-NR1A2 / THRB Antibody (Extracellular Domain) - LS-C39683 from LifeSpan Bioscience

Prices $725.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal

Anti-NR1A2 / THRB Antibody (aa354-359) - LS-C39687 from LifeSpan Bioscience

Prices $725.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal

Anti-NR1A2 / THRB Antibody (aa183-199) - LS-C55588 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-NR1A2 / THRB Antibody - LS-C92794 from LifeSpan Bioscience

Prices $530.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal
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