| Gene Symbol |
AGPAT2
|
| Entrez Gene |
10555
|
| Alt Symbol |
1-AGPAT2, BSCL, BSCL1, LPAAB, LPAAT-beta
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
1-acylglycerol-3-phosphate O-acyltransferase 2
|
| Other Description |
1-AGP acyltransferase 2|1-AGPAT 2|1-acyl-sn-glycerol-3-phosphate acyltransferase beta|1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)|lysophosphatidic acid acyltransferase beta|lysophosphatidic acid acyltransferase-beta
|
| Swissprots |
Q9BSV7 Q5VUD4 O15106 O00516 Q5VUD3 Q9BWR7 O15120
|
| Accessions |
EAW88249 EAW88250 EAW88251 EAW88252 O15120 AF000237 AAC51649 AF011374 AAB64299 BC000026 AAH00026 BC004529 AAH04529 BC007269 AAH07269 BC019292 AAH19292 BF347518 CN407343 DQ892146 ABM83072 DQ895342 ABM86268 U56418 AAB58776 NM_001012727 NP_001012745 NM_006412 NP_006403
|
| Function |
Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. {ECO:0000269|PubMed:15629135, ECO:0000269|PubMed:21873652, ECO:0000269|PubMed:9242711}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000269|PubMed:21873652}; Multi-pass membrane protein {ECO:0000269|PubMed:21873652}.
|
| Tissue Specificity |
Expressed predominantly in adipose tissue, pancreas and liver. {ECO:0000269|PubMed:21873652}.
|
| Top Pathways |
Fat digestion and absorption, Glycerolipid metabolism, Glycerophospholipid metabolism
|
![Western Blot: AGPAT2 Overexpression Lysate (Adult Normal) [NBL1-07383] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for AGPAT2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/9604_AGPAT2%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-07383-img0002.jpg)