| Gene Symbol |
Pou3f3
|
| Entrez Gene |
18993
|
| Alt Symbol |
Brn-1, Brn1, Otf8, Skin1
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
POU domain, class 3, transcription factor 3
|
| Other Description |
OTF-8|brain-1|brain-specific homeobox/POU domain protein 1|oct-8|octamer-binding protein 8|octamer-binding transcription factor 8
|
| Swissprots |
P31361
|
| Accessions |
AAA39960 P31361 BC079869 BC156037 AAI56038 CA315285 CD774392 CJ064353 NM_008900 NP_032926
|
| Function |
Transcription factor that acts synergistically with SOX11 and SOX4 (By similarity). Plays a role in neuronal development. Is implicated in an enhancer activity at the embryonic met-mesencephalic junction; the enhancer element contains the octamer motif (5'-ATTTGCAT-3'). {ECO:0000250, ECO:0000269|PubMed:10473120, ECO:0000269|PubMed:12130536, ECO:0000269|PubMed:19527706}.
|
| Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00530, ECO:0000269|PubMed:10473120}.
|
| Tissue Specificity |
Brain.
|