| Gene Symbol |
TOMM7
|
| Entrez Gene |
54543
|
| Alt Symbol |
TOM7
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
translocase of outer mitochondrial membrane 7 homolog (yeast)
|
| Other Description |
6.2 kd protein|mitochondrial import receptor subunit TOM7 homolog|translocase of outer membrane 7 kDa subunit homolog
|
| Swissprots |
Q9P0U1 O95939
|
| Accessions |
AAS01992 EAW93760 EAW93761 EAW93762 EAW93763 Q9P0U1 AA181858 AF086336 AF150733 AAF67473 AJ011007 CAB38060 AK026520 BC001732 AAH01732 BC071973 AAH71973 CR456960 CAG33241 NM_019059 NP_061932
|
| Function |
Required for assembly and stability of the TOM complex. Positive regulator of PARK2 translocation to damaged mitochondria. Acts probably by stabilizing PINK1 on the outer membrane of depolarized mitochondria. {ECO:0000269|PubMed:18331822, ECO:0000269|PubMed:24270810}.
|
| Subcellular Location |
Mitochondrion outer membrane {ECO:0000269|PubMed:12198123}; Single-pass membrane protein {ECO:0000269|PubMed:12198123}.
|
![Western Blot: TOMM7 Overexpression Lysate (Adult Normal) [NBL1-17193] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TOMM7.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5182_TOMM7%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-17193-img0002.jpg)