Gene Symbol | TOMM7 |
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Entrez Gene | 54543 |
Alt Symbol | TOM7 |
Species | Human |
Gene Type | protein-coding |
Description | translocase of outer mitochondrial membrane 7 homolog (yeast) |
Other Description | 6.2 kd protein|mitochondrial import receptor subunit TOM7 homolog|translocase of outer membrane 7 kDa subunit homolog |
Swissprots | Q9P0U1 O95939 |
Accessions | AAS01992 EAW93760 EAW93761 EAW93762 EAW93763 Q9P0U1 AA181858 AF086336 AF150733 AAF67473 AJ011007 CAB38060 AK026520 BC001732 AAH01732 BC071973 AAH71973 CR456960 CAG33241 NM_019059 NP_061932 |
Function | Required for assembly and stability of the TOM complex. Positive regulator of PARK2 translocation to damaged mitochondria. Acts probably by stabilizing PINK1 on the outer membrane of depolarized mitochondria. {ECO:0000269|PubMed:18331822, ECO:0000269|PubMed:24270810}. |
Subcellular Location | Mitochondrion outer membrane {ECO:0000269|PubMed:12198123}; Single-pass membrane protein {ECO:0000269|PubMed:12198123}. |
Tom7 CRISPR/Cas9 KO Plasmid (h) - sc-412305 from Santa Cruz Biotechnology
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Tom7 HDR Plasmid (h) - sc-412305-HDR from Santa Cruz Biotechnology
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Tom7 Double Nickase Plasmid (h) - sc-412305-NIC from Santa Cruz Biotechnology
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Tom7 Double Nickase Plasmid (h2) - sc-412305-NIC-2 from Santa Cruz Biotechnology
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Tom7 CRISPR Activation Plasmid (h) - sc-412305-ACT from Santa Cruz Biotechnology
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Tom7 CRISPR Activation Plasmid (h2) - sc-412305-ACT-2 from Santa Cruz Biotechnology
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Tom7 Lentiviral Activation Particles (h) - sc-412305-LAC from Santa Cruz Biotechnology
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Tom7 Lentiviral Activation Particles (h2) - sc-412305-LAC-2 from Santa Cruz Biotechnology
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Tom7 siRNA (h) - sc-89537 from Santa Cruz Biotechnology
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Tom7 shRNA Plasmid (h) - sc-89537-SH from Santa Cruz Biotechnology
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Tom7 shRNA (h) Lentiviral Particles - sc-89537-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN21820 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21820 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04067 from Sigma-Aldrich
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TOMM7 siRNA (Human) - CRJ0126 from Cohesion Biosciences
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TOMM7 - MBS8220252 from MyBioSource
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shRNA set against Human TOMM7 (NM_019059.3) - SHH432796 from Creative biogene
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Human TOMM7 siRNA - orb270627 from Biorbyt
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TOMM7 shRNA Plasmid (Human) - CHJ0126 from Cohesion Biosciences
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TOMM7 miRNA 3'UTR clone - MiUTR3H-09628 from Creative biogene
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