Gene Symbol | ATAD3A |
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Entrez Gene | 55210 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | ATPase family, AAA domain containing 3A |
Other Description | ATPase family AAA domain-containing protein 3A |
Swissprots | Q8N275 Q9NVI7 D2K8Q1 G3V1I6 Q96A50 Q5SV23 B3KPB3 |
Accessions | EAW56186 EAW56187 EAW56188 EAW56189 EAW56190 EAW56191 Q9NVI7 AK001571 BAA91764 AK025865 AK056099 BAG51625 AK091144 BAC03595 AK092833 AK310572 BC007803 AAH07803 BC011814 AAH11814 BC014101 AAH14101 BC033109 AAH33109 BC063607 AAH63607 DA206969 GU189416 ACZ80514 NM_001170535 NP_001164006 NM_001170536 NP_001164007 NM_018188 NP_060658 |
Function | Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level. May play an important in mitochondrial protein synthesis. May also participate in mitochondrial DNA replication. May bind to mitochondrial DNA D-loops and contribute to nucleoid stability. Required for enhanced channeling of cholesterol for hormone- dependent steroidogenesis. {ECO:0000269|PubMed:17210950, ECO:0000269|PubMed:20154147, ECO:0000269|PubMed:22453275}. |
Subcellular Location | Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion matrix, mitochondrion nucleoid. Note=In the mitochondrial inner membrane, enriched in sites with the potential to form contacts with the outer membrane. The N- terminal domain interacts with the inner surface of the mitochondrial outer membrane and the C-terminal domain localizes in a specific matrix compartment, where it is associated with nucleoids. |
Tissue Specificity | Overexpressed in lung adenocarcinomas (at protein level). {ECO:0000269|PubMed:20332122}. |
ATAD3A/B/C (A-4) - sc-376185 from Santa Cruz Biotechnology
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ATAD3A/B/C (C-16) - sc-104091 from Santa Cruz Biotechnology
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ATAD3A/B/C (H-228) - sc-292156 from Santa Cruz Biotechnology
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ATAD3A/B/C (L-15) - sc-104093 from Santa Cruz Biotechnology
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Anti-ATAD3A antibody - ab112572 from Abcam
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Anti-ATAD3A antibody - ab67992 from Abcam
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Anti-ATAD3A antibody - N-terminal - ab188386 from Abcam
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Anti-ATAD3A Antibody - LS-C306419 from LifeSpan Bioscience
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Anti-ATAD3A Antibody - LS-C309536 from LifeSpan Bioscience
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Anti-ATAD3A Antibody - LS-C309541 from LifeSpan Bioscience
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Anti-ATAD3A Antibody (aa383-432) - LS-C152091 from LifeSpan Bioscience
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Anti-ATAD3A Antibody (aa24-48) - LS-C344190 from LifeSpan Bioscience
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Anti-ATAD3A Antibody (N-Terminus) - LS-C144387 from LifeSpan Bioscience
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ATAD3A Antibody - H00055210-D01P from Novus Biologicals
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ATAD3A Antibody - H00055210-B01P from Novus Biologicals
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ATAD3A Antibody - NBP1-76586 from Novus Biologicals
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ATAD3A Antibody - NBP2-14881 from Novus Biologicals
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ATAD3A Antibody - NBP2-32331 from Novus Biologicals
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ATAD3A Antibody - H00055210-D01 from Novus Biologicals
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ATAD3A Polyclonal Antibody - bs-9108R from Bioss
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Anti-ATAD3A antibody produced in rabbit - SAB1411039 from Sigma-Aldrich
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Anti-ATAD3A antibody produced in rabbit - SAB3500668 from Sigma-Aldrich
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Anti-ATAD3A antibody produced in rabbit - SAB2701273 from Sigma-Aldrich
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Anti-ATAD3A antibody produced in mouse - SAB1400606 from Sigma-Aldrich
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ATAD3A Antibody - C-terminal region (ARP65855_P050) - ARP65855_P050 from Aviva Systems Biology
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