AGTPBP1

Gene Symbol AGTPBP1
Entrez Gene 23287
Alt Symbol CCP1, NNA1
Species Human
Gene Type protein-coding
Description ATP/GTP binding protein 1
Other Description ATP/GTP-binding protein 1|carboxypeptidase-tubulin|cytosolic carboxypeptidase 1|nervous system nuclear protein induced by axotomy protein 1 homolog|soluble carboxypeptidase|tubulinyl-Tyr carboxypeptidase|tyrosine carboxypeptidase
Swissprots Q5VV80 Q9H8U6 Q658P5 Q9NVK1 B4DRZ8 Q63HM7 Q6P9D6 Q9H9W8 Q9UPW5 B4DIT6
Accessions EAW62694 EAW62695 EAW62696 EAW62697 EAW62698 EAW62699 Q9UPW5 AB028958 BAA82987 AJ420433 AJ437018 CAD24587 AK001544 BAA91749 AK022562 BAB14100 AK023280 BAB14505 AK024698 AK295304 BAG58284 AK295774 BAG58598 AK299506 BAG61460 AL833359 CAH56222 BC060815 AAH60815 BX648366 CAH56158 CA449535 DC334722 XM_005251847 XP_005251904 XM_005251848 XP_005251905 XM_005251849 XP_005251906 XM_011518418 XP_011516720 XM_011518419 XP_011516721 XM_011518420 XP_011516722 XM_011518421 XP_011516723 NM_001286715 NP_001273644 NM_001286717 NP_001273646 NM_015239 NP_056054
Function Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5. {ECO:0000250|UniProtKB:Q641K1}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:23085998}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q641K1}. Nucleus {ECO:0000269|PubMed:23085998}. Mitochondrion {ECO:0000250|UniProtKB:Q641K1}. Note=Localizes in both the cytoplasm and nuclei of interphase and dividing cells. {ECO:0000269|PubMed:23085998}.

Nna1 Antibody - 4456 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from fetal and adult rat brain using Nna1 Antibody.

AGTPBP1 (K-13) - sc-162498 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

AGTPBP1 (S-14) - sc-162500 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

AGTPBP1 (LM-1A7) - sc-134251 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
AGTPBP1 (LM-1A7): sc-134251. Western blot analysis of AGTPBP1 expression in Hep G2 whole cell lysate.

Anti-AGTPBP1 antibody - ab77426 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-AGTPBP1 antibody (ab77426) at 1 µg/ml + Recombinant tagged human AGTPBP1 fragment at 0.2 µgSecondaryGoat anti-Mouse IgG (H&L)-HRP at 1/5000 dilution

Anti-AGTPBP1 antibody - ab68806 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-AGTPBP1 antibody (ab68806) at 1/500 dilutionLane 1 : AGTPBP1 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

Anti-AGTPBP1 antibody - ab118920 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-AGTPBP1 antibody (ab118920) at 1 µg/ml + HepG2 cell lysate at 10 µg

Anti-AGTPBP1 antibody - ab150702 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-AGTPBP1 antibody (ab150702) at 1 µg/ml + Mouse testis lysate at 10 µg

Anti-AGTPBP1 antibody [1C8] - ab128000 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1C8
All lanes : Anti-AGTPBP1 antibody [1C8] (ab128000) at 1/2000 dilutionLane 1 : HEK293T cells transfected with pCMV6-ENTRY control cDNA for 48 hrs and lysedLane 2 : HEK293T cells transfected with pCMV6-ENTRY AGTPBP1 cDNA for 48 hrs and lysed Lysates/proteins at 5 µg per lane.

Anti-AGTPBP1 antibody - N-terminal - ab173157 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-AGTPBP1 antibody - N-terminal (ab173157) at 1/100 dilution + Mouse stomach tissue lysates at 35 µg

Anti-NNA1 / AGTPBP1 Antibody - LS-C131074 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NNA1 / AGTPBP1 Antibody (aa363-392, AP) - LS-C232521 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NNA1 / AGTPBP1 Antibody (aa363-392, APC) - LS-C232520 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NNA1 / AGTPBP1 Antibody (aa363-392, PE) - LS-C232524 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NNA1 / AGTPBP1 Antibody (aa363-392, Biotin) - LS-C232523 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NNA1 / AGTPBP1 Antibody (aa363-392, FITC) - LS-C232522 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NNA1 / AGTPBP1 Antibody (aa1101-1110) - LS-C139671 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AGTPBP1 antibody (1 ug/ml) staining of HeLa lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-NNA1 / AGTPBP1 Antibody (aa1087-1187) - LS-C306143 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-NNA1 / AGTPBP1 Antibody (aa363-392, Azide-free, HRP) - LS-C249396 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NNA1 / AGTPBP1 Antibody (aa322-352) - LS-C319377 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NNA1 / AGTPBP1 Antibody (aa287-336) - LS-C116605 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
AGTPBP1 antibody LS-C116605 Western blot of HepG2 cell lysate.

Anti-NNA1 / AGTPBP1 Antibody (clone 9C8) - LS-C175226 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 9C8
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY AGTPBP1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-AGTPBP1.

Anti-NNA1 / AGTPBP1 Antibody (aa363-392) - LS-C161022 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
AGTPBP1 Antibody western blot of mouse stomach tissue lysates (35 ug/lane). The AGTPBP1 antibody detected the AGTPBP1 protein (arrow).

Anti-NNA1 / AGTPBP1 Antibody (C-Terminus) - LS-C345889 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Agtpbp1 Antibody - C-terminal region in Mouse Testis cells lysate.

Anti-NNA1 / AGTPBP1 Antibody (aa368-753, clone 1C8) - LS-C336935 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1C8
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY AGTPBP1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-AGTPBP1.
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