Gene Symbol | Coq7 |
---|---|
Entrez Gene | 12850 |
Alt Symbol | clk-1 |
Species | Mouse |
Gene Type | protein-coding |
Description | demethyl-Q 7 |
Other Description | coenzyme Q biosynthesis protein 7 homolog|timing protein clk-1 homolog|ubiquinone biosynthesis protein COQ7 homolog |
Swissprots | Q9R0D7 P97478 |
Accessions | EDL17129 EDL17130 P97478 AF053770 AAC69179 AF080580 AAC31572 AF098949 AAD43649 AK137841 AK158380 BAE34481 BC028276 AAH28276 BC038681 AAH38681 BY284216 U81277 AAC53055 XM_006507296 XP_006507359 NM_001304758 NP_001291687 NM_009940 NP_034070 |
Function | Involved in lifespan determination in ubiquinone- independent manner. Involved in ubiquinone biosynthesis. Potential central metabolic regulator. {ECO:0000269|PubMed:19478076}. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000269|PubMed:11387338}; Peripheral membrane protein {ECO:0000269|PubMed:11387338}; Matrix side {ECO:0000269|PubMed:11387338}. Note=Synthesized as a preprotein that is imported into the mitochondrial matrix, where the sequence is cleaved off and the mature protein becomes loosely associated with the inner membrane. |
Tissue Specificity | Highly expressed in tissues with high energy demand such as heart, muscle, liver, and kidney. {ECO:0000269|PubMed:11511092}. |
Top Pathways | Ubiquinone and other terpenoid-quinone biosynthesis |