Gene Symbol | Coq7 |
---|---|
Entrez Gene | 12850 |
Alt Symbol | clk-1 |
Species | Mouse |
Gene Type | protein-coding |
Description | demethyl-Q 7 |
Other Description | coenzyme Q biosynthesis protein 7 homolog|timing protein clk-1 homolog|ubiquinone biosynthesis protein COQ7 homolog |
Swissprots | Q9R0D7 P97478 |
Accessions | EDL17129 EDL17130 P97478 AF053770 AAC69179 AF080580 AAC31572 AF098949 AAD43649 AK137841 AK158380 BAE34481 BC028276 AAH28276 BC038681 AAH38681 BY284216 U81277 AAC53055 XM_006507296 XP_006507359 NM_001304758 NP_001291687 NM_009940 NP_034070 |
Function | Involved in lifespan determination in ubiquinone- independent manner. Involved in ubiquinone biosynthesis. Potential central metabolic regulator. {ECO:0000269|PubMed:19478076}. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000269|PubMed:11387338}; Peripheral membrane protein {ECO:0000269|PubMed:11387338}; Matrix side {ECO:0000269|PubMed:11387338}. Note=Synthesized as a preprotein that is imported into the mitochondrial matrix, where the sequence is cleaved off and the mature protein becomes loosely associated with the inner membrane. |
Tissue Specificity | Highly expressed in tissues with high energy demand such as heart, muscle, liver, and kidney. {ECO:0000269|PubMed:11511092}. |
Top Pathways | Ubiquinone and other terpenoid-quinone biosynthesis |
COQ7 CRISPR/Cas9 KO Plasmid (m) - sc-419762 from Santa Cruz Biotechnology
|
||||||||
COQ7 HDR Plasmid (m) - sc-419762-HDR from Santa Cruz Biotechnology
|
||||||||
COQ7 Double Nickase Plasmid (m) - sc-419762-NIC from Santa Cruz Biotechnology
|
||||||||
COQ7 Double Nickase Plasmid (m2) - sc-419762-NIC-2 from Santa Cruz Biotechnology
|
||||||||
COQ7 CRISPR Activation Plasmid (m) - sc-419762-ACT from Santa Cruz Biotechnology
|
||||||||
COQ7 CRISPR Activation Plasmid (m2) - sc-419762-ACT-2 from Santa Cruz Biotechnology
|
||||||||
COQ7 Lentiviral Activation Particles (m) - sc-419762-LAC from Santa Cruz Biotechnology
|
||||||||
COQ7 Lentiviral Activation Particles (m2) - sc-419762-LAC-2 from Santa Cruz Biotechnology
|
||||||||
COQ7 siRNA (m) - sc-62147 from Santa Cruz Biotechnology
|
||||||||
COQ7 shRNA Plasmid (m) - sc-62147-SH from Santa Cruz Biotechnology
|
||||||||
COQ7 shRNA (m) Lentiviral Particles - sc-62147-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EMU031571 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN29101 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND29101 from Sigma-Aldrich
|
||||||||
COQ7 siRNA (Mouse) - CRM0799 from Cohesion Biosciences
|
||||||||
COQ7 - MBS8200686 from MyBioSource
|
||||||||
shRNA set against Mouse COQ7 (NM_009940.2) - SHH268013 from Creative biogene
|
||||||||
shRNA set against Mouse Coq7(NM_009940.2) - SHG193355 from Creative biogene
|
||||||||
Mouse COQ7 siRNA - orb280275 from Biorbyt
|
||||||||
COQ7 shRNA Plasmid (Mouse) - CHM0799 from Cohesion Biosciences
|
||||||||
COQ7 miRNA 3'UTR clone - MiUTR1M-03245 from Creative biogene
|