| Gene Symbol |
NME5
|
| Entrez Gene |
8382
|
| Alt Symbol |
NM23-H5, NM23H5, RSPH23
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
NME/NM23 family member 5
|
| Other Description |
IPIA-beta|NDK-H 5|NDP kinase homolog 5|inhibitor of p53-induced apoptosis-beta|non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)|nucleoside diphosphate kinase homolog 5|radial spoke 23 homolog|testis-specific nm23 homolog
|
| Swissprots |
B2R5G7 P56597
|
| Accessions |
EAW62163 EAW62164 P56597 AF067724 AAC64358 AK312181 BAG35114 BC026182 AAH26182 BM979998 BX490554 U90450 AAC69440 Y14992 CAA75226 XM_005272099 XP_005272156 XM_006714716 XP_006714779 XM_011543662 XP_011541964 XM_011543663 XP_011541965 NM_003551 NP_003542
|
| Function |
Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species (By similarity). {ECO:0000250}.
|
| Tissue Specificity |
Specifically expressed in testis germinal cells.
|
| Top Pathways |
Purine metabolism, Pyrimidine metabolism
|
![Western Blot: NME5 Overexpression Lysate (Adult Normal) [NBL1-13687] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NME5.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7758_NME5%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-13687-img0002.jpg)