Gene Symbol | HPRT1 |
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Entrez Gene | 3251 |
Alt Symbol | HGPRT, HPRT |
Species | Human |
Gene Type | protein-coding |
Description | hypoxanthine phosphoribosyltransferase 1 |
Other Description | HGPRTase|hypoxanthine-guanine phosphoribosyltransferase |
Swissprots | A6NHF0 B2R8M9 P00492 |
Accessions | AAA36012 AAA52691 AAB21289 AAV31777 EAX11760 EAX11761 P00492 AK313435 BAG36226 BC000578 AAH00578 BT019350 AAV38157 CR407645 CAG28573 DQ895107 ABM86033 DQ895109 ABM86035 EU176316 ABW03767 EU176655 ABW03456 L29382 AAB59392 L29383 AAB59391 M24772 M31642 AAA52690 S60300 AAC60591 XM_011531328 XP_011529630 NM_000194 NP_000185 |
Function | Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5- phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway. |
Subcellular Location | Cytoplasm. |
Top Pathways | Purine metabolism, Drug metabolism - other enzymes |
HPRT1-Over-expression-Lysate - LY11021a from Abgent, a WuXi AppTec company
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HPRT1 overexpression lysate - LY400070 from Acris Antibodies
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HPRT1 293 Cell Lysate - 400160 from ABBIOTEC
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HPRT Overexpression Lysate (Native) - NBL1-11696 from Novus Biologicals
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HPRT (h5): 293 Lysate - sc-158621 from Santa Cruz Biotechnology
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HPRT1 Over-expression Lysate Product - GWB-3F4D23 from Genway Biotech
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HPRT Overexpression Lysate (Denatured) - H00003251-T02 from Novus Biologicals
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Panoply™ Human HPRT1 Knockdown Stable Cell Line - CSC-DC007232 from Creative biogene
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HPRT1 Knockout Cell Line-HEK293T - CSC-RT1793 from Creative biogene
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HPRT1 KO Cell Lysate-HEK293T - CLKO-1642 from Creative biogene
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