Gene Symbol | HPRT1 |
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Entrez Gene | 3251 |
Alt Symbol | HGPRT, HPRT |
Species | Human |
Gene Type | protein-coding |
Description | hypoxanthine phosphoribosyltransferase 1 |
Other Description | HGPRTase|hypoxanthine-guanine phosphoribosyltransferase |
Swissprots | A6NHF0 B2R8M9 P00492 |
Accessions | AAA36012 AAA52691 AAB21289 AAV31777 EAX11760 EAX11761 P00492 AK313435 BAG36226 BC000578 AAH00578 BT019350 AAV38157 CR407645 CAG28573 DQ895107 ABM86033 DQ895109 ABM86035 EU176316 ABW03767 EU176655 ABW03456 L29382 AAB59392 L29383 AAB59391 M24772 M31642 AAA52690 S60300 AAC60591 XM_011531328 XP_011529630 NM_000194 NP_000185 |
Function | Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5- phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway. |
Subcellular Location | Cytoplasm. |
Top Pathways | Purine metabolism, Drug metabolism - other enzymes |
HPRT CRISPR/Cas9 KO Plasmid (h) - sc-417332 from Santa Cruz Biotechnology
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HPRT HDR Plasmid (h) - sc-417332-HDR from Santa Cruz Biotechnology
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HPRT Double Nickase Plasmid (h) - sc-417332-NIC from Santa Cruz Biotechnology
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HPRT Double Nickase Plasmid (h2) - sc-417332-NIC-2 from Santa Cruz Biotechnology
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HPRT CRISPR Activation Plasmid (h) - sc-417332-ACT from Santa Cruz Biotechnology
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HPRT CRISPR Activation Plasmid (h2) - sc-417332-ACT-2 from Santa Cruz Biotechnology
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HPRT Lentiviral Activation Particles (h) - sc-417332-LAC from Santa Cruz Biotechnology
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HPRT Lentiviral Activation Particles (h2) - sc-417332-LAC-2 from Santa Cruz Biotechnology
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HPRT siRNA (h) - sc-40679 from Santa Cruz Biotechnology
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HPRT shRNA Plasmid (h) - sc-40679-SH from Santa Cruz Biotechnology
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HPRT shRNA (h) Lentiviral Particles - sc-40679-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU078931 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1266 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1266 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05675 from Sigma-Aldrich
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HPRT1 siRNA (Human) - CRH2230 from Cohesion Biosciences
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HPRT1 - MBS8212979 from MyBioSource
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shRNA set against Human Hprt (NM_000194.2) - SHH314641 from Creative biogene
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shRNA set against Human HPRT1(NM_000194.2) - SHH130259 from Creative biogene
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HPRT1 shRNA Plasmid (Human) - CHH2230 from Cohesion Biosciences
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HPRT1 miRNA 3'UTR clone - MiUTR1H-04687 from Creative biogene
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