Mapt

Gene Symbol	Mapt
Entrez Gene	29477
Alt Symbol	Mtapt, RNPTAU, pTau
Species	Rat
Gene Type	protein-coding
Description	microtubule-associated protein tau
Other Description	PHF-tau|Tau microtubule-associated protein|neurofibrillary tangle protein|paired helical filament-tau
Swissprots	P19332 Q63567 Q63677 Q9QW06
Accessions	EDM06297 EDM06298 EDM06299 EDM06300 EDM06301 EDM06302 EDM06303 EDM06304 EDM06305 EDM06306 EDM06307 EDM06308 EDM06309 EDM06310 P19332 BC126095 AAI26096 BG373604 CA945776 CB556982 CB581821 CB615367 CB726905 CB744947 CO394225 CO394568 CO405139 CO405815 D30629 DQ177309 ABA02201 DY311887 M84156 AAA42204 X79321 CAA55889 XM_008768268 XP_008766490 XM_008768269 XP_008766491 XM_008768270 XP_008766492 XM_008768271 XP_008766493 XM_008768272 XP_008766494 XM_008768273 XP_008766495 XM_008768274 XP_008766496 XM_008768275 XP_008766497 XM_008768277 XP_008766499 XM_008768278 XP_008766500 XM_008768279 XP_008766501 XM_008768280 XP_008766502 XM_008768281 XP_008766503 XM_008768282 XP_008766504 NM_017212 NP_058908
Function	Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Subcellular Location	Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Note=Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components.
Tissue Specificity	Expressed in neurons. The larger forms (isoform tau-A and isoform tau-B) are preferentially expressed in the peripheral nervous system while the other are expressed in the central nervous system. Low amounts of the larger forms are also found in limited areas of the CNS.
Top Pathways	Alzheimer's disease, MAPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Rat Mapt protein - orb245914 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Rat

Rat Mapt protein - orb244366 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Rat

Recombinant Microtubule Associated Protein Tau (MAPt) - RPB983Ra01 from Cloud-clone Category Protein Source E.coli Species Rat

Recombinant Rat Microtubule-associated protein tau(Mapt) - CSB-YP013481RA CSB-BP013481RA CSB-MP013481RA from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Rat

Recombinant Rat Microtubule-associated protein tau(Mapt) - CSB-EP013481RA from Cusabio Category Protein Source Yeast Species Rat

Mapt Recombinant Protein (OPCA01716) - OPCA01716 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Rat

Mapt Recombinant Protein (OPCA02719) - OPCA02719 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Rat

MAPT Recombinant Protein (OPCD05135) - OPCD05135 from Aviva Systems Biology Category Protein Source E.coli Species Rat

Recombinant rat Microtubule-associated protein tau - AP70532 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Rat

Recombinant rat Microtubule-associated protein tau - AP72662 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source Yeast Species Rat

Microtubule-associated protein tau, Recombinant Protein - MBS9422386 from MyBioSource Category Protein Prices $280.00, $665.00, $1,080.00, $1,690.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source Yeast Species Rat

Microtubule-associated protein tau, Recombinant Protein - MBS9420445 from MyBioSource Category Protein Prices $280.00, $665.00, $1,080.00, $1,690.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E Coli Species Rat

Microtubule-associated protein tau , Recombinant Protein - MBS965317 from MyBioSource Category Protein Prices $190.00, $460.00, $750.00, $950.00, $1,170.00, $1,180.00, $1,400.00, $1,860.00, $1,860.00, $2,760.00 Sizes 50 µg (Yeast), 200 µg (E-Coli), 500 µg (Yeast), 50 µg (Baculovirus), 50 µg (Mammalian-Cell), 1 mg (Yeast), 100 µg (Baculovirus), 100 µg (Mammalian-Cell), 500 µg (Baculovirus), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell

Recombinant Rat MAPT Protein (2-752 aa), His-tagged - MAPT-647R from Creative Biomart Category Protein Source E. coli Species Rat

Search more