Gene Symbol |
Ccr2
|
Entrez Gene |
12772
|
Alt Symbol |
Cc-ckr-2, Ccr2a, Ccr2b, Ckr2, Ckr2a, Ckr2b, Cmkbr2, mJe-r
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
chemokine (C-C motif) receptor 2
|
Other Description |
C-C CHEMOKINE RECEPTOR TYPE 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (JE/FIC RECEPTOR) (MCP-1 RECEPTOR)|C-C CKR-2|C-C chemokine receptor type 2|CCR-2|JE/FIC receptor|MCP-1 receptor|MIP-1 alphaR|chemoattractant protein-1 receptor|chemokine (C-C) receptor 2
|
Swissprots |
Q61172 P51683
|
Accessions |
EDL37176 P51683 AK039755 AK046579 BAC32793 AK138599 BAE23710 AK154590 BAE32695 AK162705 BAE37028 BC138803 AAI38804 BC138804 AAI38805 U47035 AAC52453 U51717 AAC52557 U56819 AAC52784 XM_006512426 XP_006512489 XM_006512428 XP_006512491 XM_011243063 XP_011241365 XM_011243064 XP_011241366 NM_009915 NP_034045
|
Function |
Receptor for the CCL2, CCL7 and CCL12 chemokines. Transduces a signal by increasing intracellular calcium ion levels. {ECO:0000269|PubMed:8996246}.
|
Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
Tissue Specificity |
Detected in monocyte/macrophage cell lines, but not in nonhematopoietic cell lines.
|
Top Pathways |
Cytokine-cytokine receptor interaction, Chemokine signaling pathway
|