Gene Symbol | Ccr2 |
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Entrez Gene | 12772 |
Alt Symbol | Cc-ckr-2, Ccr2a, Ccr2b, Ckr2, Ckr2a, Ckr2b, Cmkbr2, mJe-r |
Species | Mouse |
Gene Type | protein-coding |
Description | chemokine (C-C motif) receptor 2 |
Other Description | C-C CHEMOKINE RECEPTOR TYPE 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (JE/FIC RECEPTOR) (MCP-1 RECEPTOR)|C-C CKR-2|C-C chemokine receptor type 2|CCR-2|JE/FIC receptor|MCP-1 receptor|MIP-1 alphaR|chemoattractant protein-1 receptor|chemokine (C-C) receptor 2 |
Swissprots | Q61172 P51683 |
Accessions | EDL37176 P51683 AK039755 AK046579 BAC32793 AK138599 BAE23710 AK154590 BAE32695 AK162705 BAE37028 BC138803 AAI38804 BC138804 AAI38805 U47035 AAC52453 U51717 AAC52557 U56819 AAC52784 XM_006512426 XP_006512489 XM_006512428 XP_006512491 XM_011243063 XP_011241365 XM_011243064 XP_011241366 NM_009915 NP_034045 |
Function | Receptor for the CCL2, CCL7 and CCL12 chemokines. Transduces a signal by increasing intracellular calcium ion levels. {ECO:0000269|PubMed:8996246}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Detected in monocyte/macrophage cell lines, but not in nonhematopoietic cell lines. |
Top Pathways | Cytokine-cytokine receptor interaction, Chemokine signaling pathway |
C-C chemokine receptor type 2 (Ccr2), Recombinant Protein - MBS966544 from MyBioSource
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Recombinant Mouse CCR2 Protein, His-tagged - CCR2-3014M from Creative Biomart
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C-C chemokine receptor type 2 (Ccr2), Recombinant Protein - MBS7011006 from MyBioSource
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