CHRNB4

Gene Symbol CHRNB4
Entrez Gene 1143
Alt Symbol -
Species Human
Gene Type protein-coding
Description cholinergic receptor, nicotinic, beta 4 (neuronal)
Other Description acetylcholine receptor, nicotinic, beta 4 (neuronal)|cholinergic receptor, nicotinic, beta polypeptide 4|neuronal acetylcholine receptor subunit beta-4|neuronal nicotinic receptor beta 4 subunit
Swissprots Q8WXC8 P30926 E9PHE8 A4FTX5 Q4VBA5 Q9BQR4 Q16607
Accessions AAL02062 AAL57840 CAC34819 EAW99153 EAW99154 P30926 AK310443 BC096080 AAH96080 BC096081 AAH96081 BC096082 AAH96082 BC096083 AAH96083 U48861 AAA92123 U62439 AAB40117 X68275 CAA48336 Y08416 CAA69693 XM_011521181 XP_011519483 XM_011521182 XP_011519484 XM_011521183 XP_011519485 XM_011521184 XP_011519486 XM_011521185 XP_011519487 XM_011521186 XP_011519488 XM_011521187 XP_011519489 XM_011521188 XP_011519490 XM_011521189 XP_011519491 XM_011521190 XP_011519492 XM_011521191 XP_011519493 XM_011521192 XP_011519494 XM_011521193 XP_011519495 NM_000750 NP_000741 NM_001256567 NP_001243496
Function After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Subcellular Location Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Top Pathways Neuroactive ligand-receptor interaction

CHRNB4 (E-3) - sc-514315 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CHRNB4 (E-3): sc-514315. Western blot analysis of CHRNB4 expression in SH-SY5Y (A) and IMR-32 (B) whole cell lysates.

CHRNB4 (S-15) - sc-82815 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Nicotinic Acetylcholine Receptor beta 4 antibody - ab106294 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-Nicotinic Acetylcholine Receptor beta 4 antibody - ab41176 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab41176 stained SKNSH cells. The cells were 4% PFA fixed (10mins) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab41176, 1µg/ml) overnight at +4°C. The secondary antibody (green) was ab96899 Dylight 488 goat anti-rabbit IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-Nicotinic Acetylcholine Receptor beta 4 antibody - C-terminal - ab156213 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Nicotinic Acetylcholine Receptor beta 4 antibody - C-terminal (ab156213) at 1/100 dilution + 293 cell lysate at 35 µg

Anti-CHRNB4 Antibody (C-Terminus) - LS-C73557 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CHRNB4 Antibody (aa490-498) - LS-C37658 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CHRNB4 Antibody (aa490-498) - LS-C73559 from LifeSpan Bioscience

Prices $435.00
Sizes 5 ml
Host Rabbit
Clonality Polyclonal

Anti-CHRNB4 Antibody (C-Terminus) - LS-C73558 from LifeSpan Bioscience

Prices $635.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-CHRNB4 Antibody - LS-C144731 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CHRNB4 Antibody (Extracellular Domain) - LS-C126029 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CHRNB4 Antibody - LS-C153399 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CHRNB4 Antibody (aa422-450, AP) - LS-C254803 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHRNB4 Antibody (aa422-450, APC) - LS-C254804 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHRNB4 Antibody (aa422-450, Biotin) - LS-C254805 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHRNB4 Antibody (aa422-450, FITC) - LS-C254806 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHRNB4 Antibody (aa422-450) - LS-C157641 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
CHRNB4 Antibody western blot of 293 cell line lysates (35 ug/lane). The CHRNB4 antibody detected the CHRNB4 protein (arrow).

Anti-CHRNB4 Antibody (aa422-450, Azide-free, HRP) - LS-C254807 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHRNB4 Antibody (aa422-450, PE) - LS-C254808 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHRNB4 Antibody (aa422-450) - LS-C320379 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHRNB4 Antibody (Internal) IHC-plus™ - LS-B6472 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-CHRNB4 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6472 concentration 2.5 ug/ml.

Nicotinic Acetylcholine Receptor beta 4 Antibody - NBP1-18956 from Novus Biologicals

Prices $329.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Nicotinic Acetylcholine Receptor beta 4 Antibody - H00001143-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Nicotinic Acetylcholine Receptor beta 4 Antibody - NBP1-20901 from Novus Biologicals

Prices $229.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

ANTI-CHRNB4(C-TERMINAL) antibody produced in rabbit - SAB1305954 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CHRNB4 (C-term): <B>Cat. No. SAB1305954</B>: CHRNB4 Antibody (C-term) western blot analysis in 293 cell line lysates (35 μg/lane).
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