Gene Symbol |
CHRNB4
|
Entrez Gene |
1143
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
cholinergic receptor, nicotinic, beta 4 (neuronal)
|
Other Description |
acetylcholine receptor, nicotinic, beta 4 (neuronal)|cholinergic receptor, nicotinic, beta polypeptide 4|neuronal acetylcholine receptor subunit beta-4|neuronal nicotinic receptor beta 4 subunit
|
Swissprots |
Q8WXC8 P30926 E9PHE8 A4FTX5 Q4VBA5 Q9BQR4 Q16607
|
Accessions |
AAL02062 AAL57840 CAC34819 EAW99153 EAW99154 P30926 AK310443 BC096080 AAH96080 BC096081 AAH96081 BC096082 AAH96082 BC096083 AAH96083 U48861 AAA92123 U62439 AAB40117 X68275 CAA48336 Y08416 CAA69693 XM_011521181 XP_011519483 XM_011521182 XP_011519484 XM_011521183 XP_011519485 XM_011521184 XP_011519486 XM_011521185 XP_011519487 XM_011521186 XP_011519488 XM_011521187 XP_011519489 XM_011521188 XP_011519490 XM_011521189 XP_011519491 XM_011521190 XP_011519492 XM_011521191 XP_011519493 XM_011521192 XP_011519494 XM_011521193 XP_011519495 NM_000750 NP_000741 NM_001256567 NP_001243496
|
Function |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
|
Subcellular Location |
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
|
Top Pathways |
Neuroactive ligand-receptor interaction
|