Gene Symbol | SNTB2 |
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Entrez Gene | 6645 |
Alt Symbol | D16S2531E, EST25263, SNT2B2, SNT3, SNTL |
Species | Human |
Gene Type | protein-coding |
Description | syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) |
Other Description | 59 kDa dystrophin-associated protein A1 basic component 2|beta-2-syntrophin|dystrophin-associated protein A1, 59kD, basic component 2|syntrophin-3 |
Swissprots | Q13425 Q9BY09 |
Accessions | EAW83258 EAW83259 EAW83260 Q13425 AF243385 AAK15149 BC031058 BC035134 BC036429 BC048215 AAH48215 EU831451 ACE87138 EU831538 ACE86457 U40572 AAC50449 NM_006750 NP_006741 NM_130845 |
Function | Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. May play a role in the regulation of secretory granules via its interaction with PTPRN. |
Subcellular Location | Membrane. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Cell junction {ECO:0000250}. Cytoplasm, cytoskeleton. Note=Membrane-associated. In muscle, it is exclusively localized at the neuromuscular junction (By similarity). In insulinoma cell line, it is enriched in secretory granules. {ECO:0000250}. |
Tissue Specificity | Ubiquitous. Isoform 1 is the predominant isoform. Weak level of isoform 2 is present in all tested tissues, except in liver and heart where it is highly expressed. |
β2-Syntrophin (C-17) - sc-13766 from Santa Cruz Biotechnology
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Anti-SNTB2 antibody - ab67861 from Abcam
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Anti-SNTB2 Antibody (aa217-245, AP) - LS-C217664 from LifeSpan Bioscience
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Anti-SNTB2 Antibody (aa217-245, APC) - LS-C217665 from LifeSpan Bioscience
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Anti-SNTB2 Antibody (aa217-245, Biotin) - LS-C217666 from LifeSpan Bioscience
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Anti-SNTB2 Antibody (aa217-245, FITC) - LS-C217667 from LifeSpan Bioscience
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Anti-SNTB2 Antibody (aa210-259) - LS-C151497 from LifeSpan Bioscience
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Anti-SNTB2 Antibody (aa217-245, Azide-free, HRP) - LS-C217668 from LifeSpan Bioscience
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Anti-SNTB2 Antibody (aa217-245, PE) - LS-C217669 from LifeSpan Bioscience
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Anti-SNTB2 Antibody (aa216-245) - LS-C325244 from LifeSpan Bioscience
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Anti-SNTB2 Antibody (aa104-153) - LS-C187277 from LifeSpan Bioscience
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Anti-SNTB2 Antibody (clone 3F12) - LS-C198238 from LifeSpan Bioscience
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Anti-SNTB2 Antibody (aa217-245) - LS-C161360 from LifeSpan Bioscience
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Anti-SNTB2 Antibody (aa174-540) - LS-C186037 from LifeSpan Bioscience
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Syntrophin Antibody (1351) - NB600-1294 from Novus Biologicals
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SNTB2 Antibody - NBP1-85343 from Novus Biologicals
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SNTB2 Antibody - NBP1-33009 from Novus Biologicals
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SNTB2 Antibody - H00006645-B01 from Novus Biologicals
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Syntrophin Antibody (1351) [Allophycocyanin] - NB600-1294APC from Novus Biologicals
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Syntrophin Antibody (1351) [DyLight 350] - NB600-1294UV from Novus Biologicals
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Syntrophin Antibody (1351) [DyLight 488] - NB600-1294G from Novus Biologicals
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Syntrophin Antibody (1351) [DyLight 680] - NB600-1294FR from Novus Biologicals
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Syntrophin Antibody (1351) [7C] - NB600-1294V2 from Novus Biologicals
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Syntrophin Antibody (1351) [DyLight 755] - NB600-1294IR from Novus Biologicals
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Syntrophin Antibody (1351) [DyLight 405] - NB600-1294V from Novus Biologicals
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