| Gene Symbol |
SNTB2
|
| Entrez Gene |
6645
|
| Alt Symbol |
D16S2531E, EST25263, SNT2B2, SNT3, SNTL
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
|
| Other Description |
59 kDa dystrophin-associated protein A1 basic component 2|beta-2-syntrophin|dystrophin-associated protein A1, 59kD, basic component 2|syntrophin-3
|
| Swissprots |
Q13425 Q9BY09
|
| Accessions |
EAW83258 EAW83259 EAW83260 Q13425 AF243385 AAK15149 BC031058 BC035134 BC036429 BC048215 AAH48215 EU831451 ACE87138 EU831538 ACE86457 U40572 AAC50449 NM_006750 NP_006741 NM_130845
|
| Function |
Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. May play a role in the regulation of secretory granules via its interaction with PTPRN.
|
| Subcellular Location |
Membrane. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Cell junction {ECO:0000250}. Cytoplasm, cytoskeleton. Note=Membrane-associated. In muscle, it is exclusively localized at the neuromuscular junction (By similarity). In insulinoma cell line, it is enriched in secretory granules. {ECO:0000250}.
|
| Tissue Specificity |
Ubiquitous. Isoform 1 is the predominant isoform. Weak level of isoform 2 is present in all tested tissues, except in liver and heart where it is highly expressed.
|