HSPH1

Gene Symbol HSPH1
Entrez Gene 10808
Alt Symbol HSP105, HSP105A, HSP105B, NY-CO-25
Species Human
Gene Type protein-coding
Description heat shock 105kDa/110kDa protein 1
Other Description antigen NY-CO-25|heat shock 105kD alpha|heat shock 105kD beta|heat shock protein 105 kDa
Swissprots Q5TBM8 B4DYH1 Q9UPC4 Q5TBM7 O95739 Q92598 Q5TBM6
Accessions EAX08477 EAX08478 EAX08479 EAX08480 EAX08481 EAX08482 Q92598 AB003333 BAA34779 AB003334 BAA34780 AF039695 AAC18044 AK293955 BAG57329 AK302294 BAG63634 AK302430 BAG63733 AK302832 BAG64026 AK303029 BAG64155 AK307597 AK311464 AK314576 BC018124 BC037553 AAH37553 BX648125 BX648623 CD251908 D86956 BAA13192 DB069199 DB077644 DQ891727 ABM82653 DQ894904 ABM85830 XM_005266236 XP_005266293 XM_011534887 XP_011533189 XM_011534888 XP_011533190 NM_001286503 NP_001273432 NM_001286504 NP_001273433 NM_001286505 NP_001273434 NM_006644 NP_006635
Function Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:9931472}.
Tissue Specificity Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells. {ECO:0000269|PubMed:10865058, ECO:0000269|PubMed:16232202}.
Top Pathways Protein processing in endoplasmic reticulum

HSP 105 (B-7) - sc-74550 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HSP 105 (B-7): sc-74550. Western blot analysis of HSP 105 expression in untreated HeLa (A), heat shock-treated HeLa (B), untreated NIH/3T3 (C) and heat shock-treated NIH/3T3 (D) whole cell lysates.

HSP 105 (M-20) - sc-1804 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HSP 105 (M-20): sc-1804. Western blot analysis of HSP 105 expression in untreated (A) and heat shock-treated (B) NIH/3T3 whole cell lysates.

HSP 105 (N-187) - sc-6241 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
HSP 105 (N-187): sc-6241.Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization .

HSP 105 (21) - sc-135942 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
HSP 105 (21): sc-135942. Western blot analysis of HSP 105 expression in rat cerebrum tissue extract.

Anti-Hsp105 antibody - ab24503 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Hsp105 antibody (ab24503) (1 - 4 ug/ml) + HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate (ab7898)

Anti-Hsp105 antibody - ab53107 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Hsp105 antibody (ab53107) at 1/300 dilutionLane 1 : HeLa cell extractLane 2 : HeLa cell extract with immunising peptide

Anti-Hsp105 antibody - ab101005 from Abcam

Prices $376.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Hsp105 antibody (ab101005) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : Human fetal brain lysateLane 3 : Human fetal lung lysateLane 4 : Human fetal heart lysate

Anti-Hsp105 antibody - ab131072 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Hsp105 antibody (ab131072) at 0.1 µg/mlLane 1 : Rat Ovary Tissue Lysate Lane 2 : A549 Cell Lysate Lane 3 : U87 Cell Lysate Lane 4 : Hela Cell Lysate

Anti-Hsp105 antibody - ab89823 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-Hsp105 antibody (ab89823) at 1 µg/ml + human liver tissue lysate at 50 µg

Anti-Hsp105 antibody [58F12] - ab49535 from Abcam

Prices $376.00
Sizes 250 µg
Host Mouse
Clonality Monoclonal
Clone 58F12
Immunohistochemical staining of paraffin embedded human cerebellum tissue using ab49535 at 1/100 dilution, following antigen retrieval. 60 minutes primary antibody incubation at 25oC and standard ABC technique used. Note intense cytoplasmic and nuclear staining of Purkinje cells and neuronal processes.

Anti-Hsp105 antibody [EPR4576] - ab109624 from Abcam

Prices $394.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4576
All lanes : Anti-Hsp105 antibody [EPR4576] (ab109624) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : HepG2 cell lysateLane 3 : Human cerebellum lysateLane 4 : MCF-7 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled Goat anti-Rabbit at 1/2000 dilution

Anti-Hsp105 antibody [EPR4577] - ab108625 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4577
All lanes : Anti-Hsp105 antibody [EPR4577] (ab108625) at 1/10000 dilutionLane 1 : HeLa cell lysateLane 2 : HepG2 cell lysateLysates/proteins at 10 µg per lane.

Anti-Hsp105 antibody [EPR4577] (HRP) - ab201246 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4577
All lanes : Anti-Hsp105 antibody [EPR4577] (HRP) (ab201246) at 1/5000 dilutionLane 1 : HeLa (Human epithelial carcinoma cell line) Whole Cell LysateLane 2 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.developed using the ECL techniquePerformed under reducing conditions.

Anti-Hsp105 antibody [J1G12] - ab74174 from Abcam

Prices $379.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone J1G12
Anti-Hsp105 antibody [J1G12] (ab74174) at 1/1000 dilution + HeLa cell lysate at 30 µgSecondaryGoat anti mouse antibody conjugated to HRP developed using the ECL technique

Anti-Hsp105 antibody - C-terminal - ab166780 from Abcam

Prices $384.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human pancreas tissue labeling Hsp105 with ab166780 at 5 µg/ml.

Anti-HSPH1 / HSP105 Antibody - LS-C63214 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HSPH1 / HSP105 Antibody - LS-C24168 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-HSPH1 / HSP105 Antibody (aa595-733) - LS-C36620 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-HSPH1 / HSP105 Antibody (C-Terminus) - LS-C121231 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-HSPH1 / HSP105 Antibody (aa388-505) - LS-C129605 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-HSPH1 / HSP105 Antibody - LS-C137361 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-HSPH1 / HSP105 Antibody (clone J1G12) - LS-C93751 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone J1G12
Cell lysates of HeLa(30 ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human HSP105 a (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Anti-HSPH1 / HSP105 Antibody (N-Terminus) - LS-C48373 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of HSPH1 / HSP110 antibody LS-C48373.

Anti-HSPH1 / HSP105 Antibody (Atto 390) - LS-C230256 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HSPH1 / HSP105 Antibody (Atto 565) - LS-C230257 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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