FCGR3B

Gene Symbol	FCGR3B
Entrez Gene	2215
Alt Symbol	CD16, CD16b, FCG3, FCGR3, FCR-10, FCRIII, FCRIIIb
Species	Human
Gene Type	protein-coding
Description	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
Other Description	Fc-gamma receptor IIIb (CD 16)|fc-gamma RIII-beta|fc-gamma RIIIb|igG Fc receptor III-1|low affinity immunoglobulin gamma Fc region receptor III-B
Swissprots	O75015
Accessions	ACS66846 ACS66847 ACS66848 ACS66849 ACS66850 ACS66854 ACS66855 ACS66856 ACS66857 ACS66858 ACS66859 CAA86296 O75015 AB025256 BAA83803 AJ581669 CAE46408 AK313219 AK316565 BAG38154 BC128562 AAI28563 DA669913 DA670720 DA671001 DA672751 DA672763 DA673839 DC428645 DC428702 J04162 AAA35881 M24854 AAA53507 X07934 CAA30758 X16863 CAA34753 NM_000570 NP_000561 NM_001244753 NP_001231682 NM_001271035 NP_001257964 NM_001271036 NP_001257965 NM_001271037 NP_001257966
Function	Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
Subcellular Location	Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Note=Secreted after cleavage.
Tissue Specificity	Expressed specifically by polymorphonuclear leukocytes (neutrophils). Also expressed by stimulated eosinophils.
Top Pathways	Natural killer cell mediated cytotoxicity, Systemic lupus erythematosus, Leishmaniasis, Phagosome, Staphylococcus aureus infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human CD16b full length protein - ab174010 from Abcam Category Protein Prices $372.00 Sizes 100 µg Source HEK 293 cells Species Human

Human CD16b protein fragment - ab191919 from Abcam Category Protein Prices $196.00 Sizes 10 µg Source HEK 293 cells Species Human

Recombinant Human Fc gamma RIIIB/CD16b Protein - P3676 from Novus Biologicals Category Protein Prices $679.00 Sizes 20 µg Source Human Species Human

FCGR3B-Antibody-Center-Blocking-Peptide - BP8628c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human Fc gamma RIIIB/CD16b - 1597-FC-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Thr20-Gln208, with a C-terminal 10-His tag

Recombinant Human Fc gamma RIIIB/CD16b, CF - 1597-FC-050/CF from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Thr20-Gln208, with a C-terminal 10-His tag

Human FCGR3B protein - orb180268 from Biorbyt Category Protein Prices $306.00, $400.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Human CD16b His tag protein - orb82893 from Biorbyt Category Protein Prices $510.00, $748.00 Sizes 50 μg, 100 μg Source Human Species Human

Human CD16b protein - orb232255 from Biorbyt Category Protein Prices $357.00, $612.00, $893.00 Sizes 20 μg, 50 μg, 100 μg Species Human

Human CD16b protein (His Tag) - orb138363 from Biorbyt Category Protein Prices $323.00, $612.00 Sizes 20 μg, 50 μg Source CHO Cells Species Human

Human FcgR3B Protein - abx066544 from Abbexa Category Protein Source E.coli Species Human

CD16b - P3676 from Acris Antibodies Category Protein Prices $580.00 Sizes 20 µg Species Human

Fc gamma RIIIB Recombinant Protein - 96-154 from ProSci Category Protein Prices $375.00 Sizes 100 µg Source HEK293 cells Species Human

Recombinant Human Fc gamma RIIIB Protein - BP4100 from Syd Labs Category Protein Prices $550.00 Sizes 100 µg Source HEK 293 cell-derived. Species Human

Recombinant Human FCGR3B, His tagged - FCGR3B-3198H from Creative Biomart Category Protein Source Human Cells Species Human

Recombinant Human FCGR3B, None tagged - FCGR3B-3869H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human FCGR3B, His tagged - FCGR3B-7309H from Creative Biomart Category Protein Source CHO Cells Species Human

Recombinant Human FCGR3B, His-tagged, Biotinylated - FCGR3B-260H from Creative Biomart Category Protein Source HEK293 Species Human

Recombinant Human FCGR3B, His-tagged - FCGR3B-1022H from Creative Biomart Category Protein Source NSO Cells Species Human

Human CD16b Recombinant (FcgR3b) - RKO75015 from Reprokine Category Protein Prices $160.00, $480.00, $1,650.00 Sizes 20 µg, 100 µg, 500 µg Source Optimized DNA sequence encoding Human extracellular domain of human CD16b including a C-terminal 6His tag was expressed in HEK293 cells. Species Human

Human CD16b Recombinant (FcgR3b), Biotinylated - RBO75015 from Reprokine Category Protein Prices $340.00, $590.00, $1,950.00 Sizes 10 µg, 25 µg, 100 µg Source Optimized DNA sequence encoding Human extracellular domain of human CD16b including a C-terminal 6His tag was expressed in HEK293 cells. CD16b was further labled by Biotin for detection by avidin conjugated secondary probes Species Human

Recombinant Fc Fragment Of IgG Low Affinity IIIb Receptor (FcgR3B) - RPB271Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Human CD16b / FCGR3B Protein (His Tag) - 11046-H08C-20 from Sino Biological Category Protein Source CHO Cells Species Human

Human Fc gamma RIIIB / CD16b Protein - CDB-H5222 from ACROBiosystems Category Protein Prices $260.00, $1,600.00 Sizes 100 µg, 1 mg (500ug x 2) Source Human Fc gamma RIIIB / CD16b Protein (Human Fc gamma RIIIB/CD16b, His Tag) Gly 17 - Ser 200 (Accession # AAI28563.1) was produced in human 293 cells (HEK293) at ACROBiosystems. Species Human

Recombinant Fc Fragment Of IgG Low Affinity IIIb Receptor (FcgR3B) - RPB271Hu01 from Cloud-clone Category Protein Source E.coli Species Human

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