FCGR3B

Gene Symbol FCGR3B
Entrez Gene 2215
Alt Symbol CD16, CD16b, FCG3, FCGR3, FCR-10, FCRIII, FCRIIIb
Species Human
Gene Type protein-coding
Description Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
Other Description Fc-gamma receptor IIIb (CD 16)|fc-gamma RIII-beta|fc-gamma RIIIb|igG Fc receptor III-1|low affinity immunoglobulin gamma Fc region receptor III-B
Swissprots O75015
Accessions ACS66846 ACS66847 ACS66848 ACS66849 ACS66850 ACS66854 ACS66855 ACS66856 ACS66857 ACS66858 ACS66859 CAA86296 O75015 AB025256 BAA83803 AJ581669 CAE46408 AK313219 AK316565 BAG38154 BC128562 AAI28563 DA669913 DA670720 DA671001 DA672751 DA672763 DA673839 DC428645 DC428702 J04162 AAA35881 M24854 AAA53507 X07934 CAA30758 X16863 CAA34753 NM_000570 NP_000561 NM_001244753 NP_001231682 NM_001271035 NP_001257964 NM_001271036 NP_001257965 NM_001271037 NP_001257966
Function Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
Subcellular Location Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Note=Secreted after cleavage.
Tissue Specificity Expressed specifically by polymorphonuclear leukocytes (neutrophils). Also expressed by stimulated eosinophils.
Top Pathways Natural killer cell mediated cytotoxicity, Systemic lupus erythematosus, Leishmaniasis, Phagosome, Staphylococcus aureus infection

CD16-B CRISPR/Cas9 KO Plasmid (h) - sc-417469 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD16-B HDR Plasmid (h) - sc-417469-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD16-B Double Nickase Plasmid (h) - sc-417469-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD16-B Double Nickase Plasmid (h2) - sc-417469-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD16-B CRISPR Activation Plasmid (h) - sc-417469-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD16-B CRISPR Activation Plasmid (h2) - sc-417469-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD16-B Lentiviral Activation Particles (h) - sc-417469-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD16-B Lentiviral Activation Particles (h2) - sc-417469-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD16-B siRNA (h) - sc-42760 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CD16-B shRNA Plasmid (h) - sc-42760-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CD16-B shRNA (h) Lentiviral Particles - sc-42760-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Fc gamma RIIIB/CD16b RNAi - H00002215-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN8593 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8593 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

FCGR3B siRNA (Human) - CRH1549 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FCGR3B - MBS8227202 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human FCGR3B (NM_000570.4) - SHH293753 from Creative biogene

Category siRNA
Species Reactivities Human

Human FCGR3B siRNA - orb262051 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FCGR3B shRNA Plasmid (Human) - CHH1549 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FCGR3B miRNA 3'UTR clone - MiUTR3H-11401 from Creative biogene

Species Reactivities Human
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